Regulated forms of cell death in fungi
Cell death occurs in all domains of life. While some cells die in an uncontrolled way due to
exposure to external cues, other cells die in a regulated manner as part of a genetically …
exposure to external cues, other cells die in a regulated manner as part of a genetically …
Fungal cell death: the beginning of the end
AM Rico-Ramírez, AP Gonçalves, NL Glass - Fungal Genetics and Biology, 2022 - Elsevier
Death is an important part of an organism's existence and also marks the end of life. On a
cellular level, death involves the execution of complex processes, which can be classified …
cellular level, death involves the execution of complex processes, which can be classified …
Discovery of EMRE in fungi resolves the true evolutionary history of the mitochondrial calcium uniporter
Abstract Calcium (Ca2+) influx into mitochondria occurs through a Ca2+-selective uniporter
channel, which regulates essential cellular processes in eukaryotic organisms. Previous …
channel, which regulates essential cellular processes in eukaryotic organisms. Previous …
MICU1 confers protection from MCU-dependent manganese toxicity
The mitochondrial calcium uniporter is a highly selective ion channel composed of species-
and tissue-specific subunits. However, the functional role of each component still remains …
and tissue-specific subunits. However, the functional role of each component still remains …
Neurospora crassa transcriptomics reveals oxidative stress and plasma membrane homeostasis biology genes as key targets in response to chitosan
F Lopez-Moya, D Kowbel, MJ Nueda… - Molecular …, 2016 - pubs.rsc.org
Chitosan is a natural polymer with antimicrobial activity. Chitosan causes plasma membrane
permeabilization and induction of intracellular reactive oxygen species (ROS) in Neurospora …
permeabilization and induction of intracellular reactive oxygen species (ROS) in Neurospora …
Role of calcium in reactive oxygen species-induced apoptosis in Candida albicans: an antifungal mechanism of antimicrobial peptide, PMAP-23
S Kim, DG Lee - Free Radical Research, 2019 - Taylor & Francis
Abstract PMAP-23 (RIIDLLWRVRRPQKPKFVTVWVR-NH2) is an antimicrobial peptide
(AMP) derived from porcine myeloid. Membrane disruption is thought to underpin the …
(AMP) derived from porcine myeloid. Membrane disruption is thought to underpin the …
Drugs currently under investigation for the treatment of invasive candidiasis
MW McCarthy, TJ Walsh - Expert opinion on investigational drugs, 2017 - Taylor & Francis
Introduction: The widespread implementation of immunosuppressants, immunomodulators,
hematopoietic stem cell transplantation and solid organ transplantation in clinical practice …
hematopoietic stem cell transplantation and solid organ transplantation in clinical practice …
Ca2+ Signalling Differentially Regulates Germ-Tube Formation and Cell Fusion in Fusarium oxysporum
Fusarium oxysporum is an important plant pathogen and an emerging opportunistic human
pathogen. Germination of conidial spores and their fusion via conidial anastomosis tubes …
pathogen. Germination of conidial spores and their fusion via conidial anastomosis tubes …
Functional diversity of complex I subunits in Candida albicans mitochondria
D Li, X She, R Calderone - Current genetics, 2016 - Springer
Our interest in the mitochondria of Candida albicans has progressed to the identification of
several proteins that are critical to complex I (CI) activity. We speculated that there should be …
several proteins that are critical to complex I (CI) activity. We speculated that there should be …
Evolutionary divergence reveals the molecular basis of EMRE dependence of the human MCU
MJS MacEwen, AL Markhard… - Life Science …, 2020 - life-science-alliance.org
The mitochondrial calcium uniporter (MCU) is a calcium-activated calcium channel critical
for signaling and bioenergetics. MCU, the pore-forming subunit of the uniporter, contains two …
for signaling and bioenergetics. MCU, the pore-forming subunit of the uniporter, contains two …