1H-Pyrazolo[3,4-b]pyridines: Synthesis and Biomedical Applications

A Donaire-Arias, AM Montagut, R Puig de la Bellacasa… - Molecules, 2022 - mdpi.com
Pyrazolo [3, 4-b] pyridines are a group of heterocyclic compounds presenting two possible
tautomeric forms: the 1 H-and 2 H-isomers. More than 300,000 1 H-pyrazolo [3, 4-b] …

C3‐Functionalized Chromones Synthesis by Tandem C− H Elaboration and Chromone Annulation of Enaminones

L Fu, JP Wan - Asian Journal of Organic Chemistry, 2019 - Wiley Online Library
Chromone is a heterocyclic entity presents in a number of natural products, clinical
pharmaceuticals, as well as molecules with enriched biological functions. As cutting‐edge …

Electrochemical synthesis of enaminones via a decarboxylative coupling reaction

X Kong, Y Liu, L Lin, Q Chen, B Xu - Green Chemistry, 2019 - pubs.rsc.org
An environmentally benign and efficient electrochemical synthesis of enaminones via a
decarboxylative coupling reaction of α-keto acids using n-Bu4NI as a redox catalyst and …

Domino Approach to Heterocycles-Based Unsymmetrical Triarylmethanes through Heteroannulation of 2-(2-Enynyl)-pyridines with Enaminones

F Ahmad, PK Ranga, S Fatma… - The Journal of Organic …, 2024 - ACS Publications
Herein, we report a copper-catalyzed protocol to access unsymmetrical triarylmethanes
containing both indolizine and the chromone scaffolds in the same molecule via a 5-endo …

A study in scaffold hopping: discovery and optimization of Thiazolopyridines as potent herbicides that inhibit acyl-ACP Thioesterase

SAG Abel, N Alnafta, E Asmus… - Journal of Agricultural …, 2023 - ACS Publications
In the search for new chemical entities that can control resistant weeds by addressing novel
modes of action (MoAs), we were interested in further exploring a compound class that …

Synthesis of enaminones via copper-catalyzed decarboxylative coupling reaction under redox-neutral conditions

Z Zhu, X Tang, J Li, X Li, W Wu, G Deng… - Chemical …, 2017 - pubs.rsc.org
A novel copper-catalyzed C (sp3)–H oxidative functionalization of aromatic oxime acetates
with α-oxocarboxylic acids was reported. This process involved N–O/C–C bond cleavages …

Furo [3, 2-c] coumarins carrying carbon substituents at C-2 and/or C-3. Isolation, biological activity, synthesis and reaction mechanisms

I Cortés, LJ Cala, ABJ Bracca, TS Kaufman - RSC advances, 2020 - pubs.rsc.org
The isolation, biological activity and synthesis of natural furo [3, 2-c] coumarins are
presented, covering mainly the developments in the last 35 years. The most relevant …

An approach towards the synthesis of novel fused nitrogen tricyclic heterocyclic scaffolds via GBB reaction

SG Balwe, YT Jeong - Organic & biomolecular chemistry, 2018 - pubs.rsc.org
A concise and efficient one-pot synthesis of novel N-fused tricyclic derivatives has been
developed by using the Groebke–Blackburn–Bienaymé (GBB) reaction, which involved the …

Oxidative regioselective amination of chromones exposes potent inhibitors of the hedgehog signaling pathway

R Samanta, R Narayan, JO Bauer… - Chemical …, 2015 - pubs.rsc.org
A transition metal-free, oxidative, regioselective cross-coupling between non-functionalized
azoles and chromones at C2-position was developed. A broad reaction scope and further …

A domino reaction of 3-chlorochromones with aminoheterocycles. Synthesis of pyrazolopyridines and benzofuropyridines and their optical and ecto-5′-nucleotidase …

M Miliutina, J Janke, S Hassan, S Zaib… - Organic & …, 2018 - pubs.rsc.org
A new and efficient domino reaction of 3-chlorochromones with electron-rich
aminoheterocycles was developed which allows for a convenient synthesis of a variety of …