[HTML][HTML] Biological effects and medical applications of infrared radiation

SR Tsai, MR Hamblin - Journal of Photochemistry and Photobiology B …, 2017 - Elsevier
Infrared (IR) radiation is electromagnetic radiation with wavelengths between 760 nm and
100,000 nm. Low-level light therapy (LLLT) or photobiomodulation (PBM) therapy generally …

Carotenoids in human skin in vivo: Antioxidant and photo-protectant role against external and internal stressors

ME Darvin, J Lademann, J von Hagen, SB Lohan… - Antioxidants, 2022 - mdpi.com
The antioxidant system of the human body plays a crucial role in maintaining redox
homeostasis and has an important protective function. Carotenoids have pronounced …

Depth profiles of hydrogen bound water molecule types and their relation to lipid and protein interaction in the human stratum corneum in vivo

CS Choe, J Lademann, ME Darvin - Analyst, 2016 - pubs.rsc.org
Confocal Raman microscopy has been used to measure depth-dependent profiles of human
SC in vivo in the high wavenumber (HWN) region. In order to keep the linearity of HWN …

Smart biomaterials and their potential applications in tissue engineering

HM Khan, X Liao, BA Sheikh, Y Wang, Z Su… - Journal of Materials …, 2022 - pubs.rsc.org
Smart biomaterials have been rapidly advancing ever since the concept of tissue
engineering was proposed. Interacting with human cells, smart biomaterials can play a key …

Keratin-water-NMF interaction as a three layer model in the human stratum corneum using in vivo confocal Raman microscopy

CS Choe, J Schleusener, J Lademann, ME Darvin - Scientific reports, 2017 - nature.com
The secondary and tertiary structure of keratin and natural moisturizing factor (NMF) are of
great importance regarding the water regulating functions in the stratum corneum (SC). In …

Optical methods for non-invasive determination of skin penetration: current trends, advances, possibilities, prospects, and translation into in vivo human studies

ME Darvin - Pharmaceutics, 2023 - mdpi.com
Information on the penetration depth, pathways, metabolization, storage of vehicles, active
pharmaceutical ingredients (APIs), and functional cosmetic ingredients (FCIs) of topically …

Blue‐violet light irradiation dose dependently decreases carotenoids in human skin, which indicates the generation of free radicals

S Vandersee, M Beyer, J Lademann… - … medicine and cellular …, 2015 - Wiley Online Library
In contrast to ultraviolet and infrared irradiation, which are known to facilitate cutaneous
photoaging, immunosuppression, or tumour emergence due to formation of free radicals and …

Hydrogen bound water profiles in the skin influenced by optical clearing molecular agents—Quantitative analysis using confocal Raman microscopy

AY Sdobnov, ME Darvin, J Schleusener… - Journal of …, 2019 - Wiley Online Library
Confocal Raman microscopy has been used to measure depth‐dependent profiles of
porcine skin ex vivo in the high wavenumber region after application of molecular optical …

Human skin in vivo has a higher skin barrier function than porcine skin ex vivo—comprehensive Raman microscopic study of the stratum corneum

CS Choe, J Schleusener, J Lademann… - Journal of …, 2018 - Wiley Online Library
Porcine skin is widely used as a human skin model in dermatology. For both, porcine
stratum corneum (SC) ex vivo and human SC in vivo, the hydrogen bonding states of water …

Melanin distribution from the dermal–epidermal junction to the stratum corneum: non-invasive in vivo assessment by fluorescence and Raman microspectroscopy

BP Yakimov, EA Shirshin, J Schleusener… - Scientific reports, 2020 - nature.com
The fate of melanin in the epidermis is of great interest due to its involvement in numerous
physiological and pathological processes in the skin. Melanin localization can be assessed …