Recent contributions from the Baylis− Hillman reaction to organic chemistry

D Basavaiah, BS Reddy, SS Badsara - Chemical reviews, 2010 - ACS Publications
Organic synthesis is one of the most successful and useful disciplines of science and mainly
involves the construction of carbon-carbon bond (s) and carbon-heteroatom bond (s) and …

Synthesis of novel functionalized 3-spiropyrrolizidine and 3-spiropyrrolidine oxindoles from baylis− hillman adducts of isatin and heteroaldehydes with azomethine …

P Shanmugam, B Viswambharan, S Madhavan - Organic Letters, 2007 - ACS Publications
Synthesis of Novel Functionalized 3-Spiropyrrolizidine and 3-Spiropyrrolidine Oxindoles
from Baylis−Hillman Adducts of Isatin and Heteroaldehydes with Azomethine Ylides via [3+2]-Cycloaddition …

[图书][B] The chemistry of the Morita-Baylis-Hillman reaction

M Shi, F Wang, MX Zhao, Y Wei - 2011 - books.google.com
Carbon-carbon bond formations and functional group transformations are the most
fundamental reactions for the construction of molecular frameworks and are at the forefront …

Synthesis of 5-aryl-3, 3′-bis-indolyl and bis-7-aza-indolyl methanone derivatives from 5-bromo-7-azaindoles via sequential methylenation using microwave …

E Pavithra, S Kannadasan, P Shanmugam - RSC advances, 2022 - pubs.rsc.org
A catalyst-free and green chemical method has been developed for the methylenation of
indole and N-methyl-7-aza indoles with aqueous formaldehyde afforded respective N, N …

A facile and efficient synthesis of highly functionalised 3, 3′-dispiropyrrolidine-and 3, 3′-dispiropyrrolizidine bisoxindoles via [3+ 2] cycloaddition

P Shanmugam, B Viswambharan, K Selvakumar… - Tetrahedron …, 2008 - Elsevier
The [3+ 2] cycloaddition reaction of azomethine ylides with isomerised Morita–Baylis–
Hillman adducts, both dipoles and dipolarophiles are derived from isatin, afforded highly …

Azomethine ylide [3+ 2]-cycloaddition of 3-alkylidene-7-aza-2-indolone: Synthesis of 3, 3′-dispiropyrrolidine-and 3, 3′-dispiropyrrolizidine bis 7-aza-2-oxindoles

RK Preethi, S Kannadasan, P Shanmugam - Tetrahedron Letters, 2023 - Elsevier
Abstract 32 AY CA reactions of 3-alkylidene-7-aza-2-indalone with acyclic and cyclic AY's
generated in situ from 7-azaisatin/isatin and sarcosine/proline in the presence of …

Catalytic asymmetric synthesis of 3-hydroxyl-2-oxindoles via enantioselective Morita–Baylis–Hillman reaction of isatins

CC Wang, XY Wu - Tetrahedron, 2011 - Elsevier
The enantioselective Morita–Baylis–Hillman reaction of acrylates to isatins was investigated
for the first time, employing bifunctional phosphinothiourea organocatalysts based on chiral …

Stereoselective synthesis of 3-spiro-α-methylene-γ-butyrolactone oxindoles from Morita–Baylis–Hillman adducts of isatin

P Shanmugam, V Vaithiyanathan - Tetrahedron, 2008 - Elsevier
A concise stereoselective synthesis of 3-spiro-α-methylene-γ-butyrolactone oxindoles from
Morita–Baylis–Hillman adducts of isatin in excellent yield has been achieved following a …

Synthesis of substituted isatins from the MBH adduct of 1, 5, 6-trisubstituted isatins using (2, 4-dinitrophenyl) hydrazine and K-10 clay explored as protection …

V Vadivel, R Ganesan, V Kannaiyan, E Vellikannu… - ACS …, 2019 - ACS Publications
An interesting synthetic transformation of protection–deprotection chemistry in an isatin
molecule is achieved. Morita–Baylis–Hillman (MBH) adduct formation used as protection of …

A Short and Efficient Synthesis of 3-Spiro-α-methylene-γ-butyrolactone Oxindolones from Isomerised Bromo Derivatives of Morita-Baylis-Hillman Adducts

P Shanmugam, B Viswambharan - Synlett, 2008 - thieme-connect.com
A short and efficient synthesis of α-methylene-γ-butyrolactone-3-spirooxindolones by the
reaction of isomerised bromo derivatives of Morita-Baylis-Hillman adducts of isatin and …