Live porcine reproductive and respiratory syndrome virus vaccines: current status and future direction

GJ Renukaradhya, XJ Meng, JG Calvert, M Roof… - Vaccine, 2015 - Elsevier
Porcine reproductive and respiratory syndrome (PRRS) caused by PRRS virus (PRRSV)
was reported in the late 1980s. PRRS still is a huge economic concern to the global pig …

Adjuvants for swine vaccines: Mechanisms of actions and adjuvant effects

W Charerntantanakul - Vaccine, 2020 - Elsevier
This review deals with mechanisms of actions (MOA) and adjuvant effects of various types of
adjuvants for swine vaccines. A number of different types of adjuvants have been tested with …

Characterization of homologous and heterologous adaptive immune responses in porcine reproductive and respiratory syndrome virus infection

I Díaz, M Gimeno, L Darwich, N Navarro… - Veterinary …, 2012 - Springer
The present study characterized the homologous and heterologous immune response in
type-I porcine reproductive and respiratory syndrome virus (PRRSV) infection. Two …

Effect of mucosal adjuvant IL-1β on heterotypic immunity in a pig influenza model

A Schmidt, B Paudyal… - Frontiers in …, 2023 - frontiersin.org
T cell responses directed against highly conserved viral proteins contribute to the clearance
of the influenza virus and confer broadly cross-reactive and protective immune responses …

The NN non-covalent domain of the nucleocapsid protein of type 2 porcine reproductive and respiratory syndrome virus enhances induction of IL-10 expression

X Liu, B Fan, J Bai, H Wang, Y Li… - Journal of General …, 2015 - microbiologyresearch.org
Porcine reproductive and respiratory syndrome virus (PRRSV) usually establishes a
prolonged infection and causes an immunosuppressive state. It has been proposed that IL …

Rescue and evaluation of a recombinant PRRSV expressing porcine Interleukin-4

Z Li, G Wang, Y Wang, C Zhang, X Wang, B Huang… - Virology Journal, 2015 - Springer
Background The current vaccines for porcine reproductive and respiratory syndrome virus
(PRRSV) have failed to provide broad protection against infection by various strains of …

Immune responses of pigs immunized with a recombinant porcine reproductive and respiratory syndrome virus expressing porcine GM-CSF

Z Li, G Wang, Y Wang, C Zhang, B Huang, Q Li… - Veterinary Immunology …, 2015 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) has spread worldwide,
causing huge economic losses to the swine industry. The current PRRSV vaccines have …

Construction and immunogenicity evaluation of an epitope-based antigen against swine influenza A virus using Escherichia coli heat-labile toxin B subunit as a carrier …

Z Sun, S Lawson, R Langenhorst, KL McCormick… - Veterinary …, 2013 - Elsevier
Influenza A virus causes a highly contagious respiratory disease in a variety of avian and
mammalian hosts, including humans and pigs. The primary means for preventing influenza …

Construction and in vitro evaluation of a recombinant live attenuated PRRSV expressing GM-CSF

L Yu, Y Zhou, Y Jiang, W Tong, S Yang, F Gao, K Wang… - Virology journal, 2014 - Springer
Background Porcine reproductive and respiratory syndrome virus (PRRSV) continues to be
an important problem for the swine industry. Inactivated vaccines and modified-live virus …

Attenuation of highly pathogenic porcine reproductive and respiratory syndrome virus by inserting an additional transcription unit

L Wang, J Hou, L Gao, X Guo, Z Yu, Y Zhu, Y Liu… - Vaccine, 2014 - Elsevier
Transcription regulatory sequences (TRSs) play a key role in the synthesis of porcine
reproductive and respiratory syndrome virus (PRRSV) subgenomic mRNAs, which …