Immune evasion and provocation by Mycobacterium tuberculosis

P Chandra, SJ Grigsby, JA Philips - Nature Reviews Microbiology, 2022 - nature.com
Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humans for
millennia. M. tuberculosis is well adapted to establish infection, persist in the face of the host …

The fluid dynamics of disease transmission

L Bourouiba - Annual Review of Fluid Mechanics, 2021 - annualreviews.org
For an infectious disease such as the coronavirus disease 2019 (COVID-19) to spread,
contact needs to be established between an infected host and a susceptible one. In a range …

Somatosensory and autonomic neuronal regulation of the immune response

S Udit, K Blake, IM Chiu - Nature Reviews Neuroscience, 2022 - nature.com
Bidirectional communication between the peripheral nervous system (PNS) and the immune
system is a crucial part of an effective but balanced mammalian response to invading …

Internal senses of the vagus nerve

SL Prescott, SD Liberles - Neuron, 2022 - cell.com
The vagus nerve is an indispensable body-brain connection that controls vital aspects of
autonomic physiology like breathing, heart rate, blood pressure, and gut motility, reflexes …

Fluid dynamics of respiratory infectious diseases

L Bourouiba - Annual review of biomedical engineering, 2021 - annualreviews.org
The host-to-host transmission of respiratory infectious diseases is fundamentally enabled by
the interaction of pathogens with a variety of fluids (gas or liquid) that shape pathogen …

Pathogenicity and virulence of Mycobacterium tuberculosis

KC Rahlwes, BRS Dias, PC Campos… - Virulence, 2023 - Taylor & Francis
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, an infectious
disease with one of the highest morbidity and mortality rates worldwide. Leveraging its …

Drug resistant tuberculosis: Implications for transmission, diagnosis, and disease management

D Liebenberg, BG Gordhan, BD Kana - Frontiers in cellular and …, 2022 - frontiersin.org
Drug resistant tuberculosis contributes significantly to the global burden of antimicrobial
resistance, often consuming a large proportion of the healthcare budget and associated …

S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis

L Deng, F Costa, KJ Blake, S Choi, A Chandrabalan… - Cell, 2023 - cell.com
Itch is an unpleasant sensation that evokes a desire to scratch. The skin barrier is constantly
exposed to microbes and their products. However, the role of microbes in itch generation is …

How do sensory neurons sense danger signals?

CR Donnelly, O Chen, RR Ji - Trends in neurosciences, 2020 - cell.com
Sensory neurons are activated by physical and chemical stimuli, eliciting sensations such as
temperature, touch, pain, and itch. From an evolutionary perspective, sensing danger is …

Neurobiology of SARS-CoV-2 interactions with the peripheral nervous system: implications for COVID-19 and pain

AJ McFarland, MS Yousuf, S Shiers, TJ Price - Pain reports, 2021 - journals.lww.com
SARS-CoV-2 is a novel coronavirus that infects cells through the angiotensin-converting
enzyme 2 receptor, aided by proteases that prime the spike protein of the virus to enhance …