Abstract Serotonin (5-hydroxytryptamine, 5-HT) is an intrinsically fluorescent
neurotransmitter found in organisms spanning a wide evolutionary range. Serotonin exerts …

G protein-coupled receptors (GPCRs) are the largest and a diverse family of proteins
involved in signal transduction across biological membranes. GPCRs mediate a wide range …

Serotonin (5-HT) is a vital modulatory neurotransmitter responsible for regulating most
behaviors in the brain. An inefficient 5-HT synaptic function is often linked to various mental …

Biological membranes are complex organized molecular assemblies of lipids and proteins
that provide cells and membrane-bound intracellular organelles their individual identities by …

Melatonin, the hormone of darkness, is secreted in minute amounts during the night and is
virtually undetectable during the day. Melatonin mainly acts on high-affinity G protein …

G protein-coupled receptors (GPCRs) are the largest class of membrane proteins involved in
signal transduction and are characterized by seven transmembrane domain architecture …

Alcohol use disorder and depression show a high comorbidity at clinical level with no
treatment available selectively for this condition. A hyperfunction of acid sphingomyelinase …

Biological membranes allow morphological compartmentalization of cells and represent
complex micro-heterogeneous fluids exhibiting a range of dynamics. The plasma membrane …

Structural transitions involving shape changes play an important role in cellular physiology.
Charged micelles offer a convenient model system in which structural transitions can be …

Cholesterol is an important lipid in the context of membrane protein function. The function of
a number of membrane proteins, including G protein-coupled receptors (GPCRs) and ion …