Molecular recognition at the biointerface plays a critical role in sensing molecular
interactions (eg, DNA hybridization) and extracellular changes, which can directly affect the …

This Review focuses on how to use DNA nanostructures as scaffolds to organize biological
molecules. First, we introduce the use of structural DNA nanotechnology to engineer …

INTRODUCTION Synthetic DNA can be programmed by using canonical Watson-Crick base
pairing to form highly structured nanometer-scale assemblies that rival many natural protein …

The blooming field of structural DNA nanotechnology harnessing the material properties of
nucleic acids has attracted widespread interest. The exploitation of the precise and …

Structural DNA nanotechnology,,, and the DNA origami technique, in particular, have
provided a range of spatially addressable two-and three-dimensional nanostructures …

DNA cages are nanometer-scale polyhedral structures formed by self-assembly from
synthetic DNA oligonucleotides. Potential applications include in vivo imaging and the …

We introduce an extended version of oxDNA, a coarse-grained model of deoxyribonucleic
acid (DNA) designed to capture the thermodynamic, structural, and mechanical properties of …

Molecular self-assembly with nucleic acids can be used to fabricate discrete objects with
defined sizes and arbitrary shapes,. It relies on building blocks that are commensurate to …

The organization of biological materials into versatile three-dimensional assemblies could
be used to build multifunctional therapeutic scaffolds for use in nanomedicine. Here, we …

A key goal for nanotechnology is to design synthetic objects that may ultimately achieve
functionalities known today only from natural macromolecular complexes. Molecular self …