APOA1: a protein with multiple therapeutic functions

BJ Cochran, KL Ong, B Manandhar, KA Rye - Current Atherosclerosis …, 2021 - Springer
Abstract Purpose of the Review Apolipoprotein (APO) A1, the main apolipoprotein of plasma
high-density lipoproteins (HDLs), has several well documented cardioprotective functions. A …

Periodontal systemic associations: review of the evidence

GJ Linden, A Lyons… - Journal of periodontology, 2013 - Wiley Online Library
Aim: To critically appraise recent research into associations between periodontal disease
and systemic diseases and conditions specifically respiratory disease, chronic kidney …

Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

MJ Chapman, HN Ginsberg, P Amarenco… - European heart …, 2011 - academic.oup.com
Even at low-density lipoprotein cholesterol (LDL-C) goal, patients with cardiometabolic
abnormalities remain at high risk of cardiovascular events. This paper aims (i) to critically …

Obesity, adiposity, and dyslipidemia: a consensus statement from the National Lipid Association

HE Bays, PP Toth, PM Kris-Etherton, N Abate… - Journal of clinical …, 2013 - Elsevier
The term “fat” may refer to lipids as well as the cells and tissue that store lipid (ie, adipocytes
and adipose tissue).“Lipid” is derived from “lipos,” which refers to animal fat or vegetable oil …

Animal models of atherosclerosis

GS Getz, CA Reardon - Arteriosclerosis, thrombosis, and vascular …, 2012 - Am Heart Assoc
Atherosclerosis is a chronic inflammatory disorder that is the underlying cause of most
cardiovascular disease. Both cells of the vessel wall and cells of the immune system …

HDL-targeted therapies: progress, failures and future

BA Kingwell, MJ Chapman, A Kontush… - Nature reviews Drug …, 2014 - nature.com
Since the discovery in the 1970s that plasma levels of high-density lipoprotein cholesterol
(HDL-C) are inversely associated with cardiovascular outcome, it has been postulated that …

Evidence that periodontal treatment improves biomarkers and CVD outcomes

F D'Aiuto, M Orlandi, JC Gunsolley - Journal of periodontology, 2013 - Wiley Online Library
Aim: The aim of this review was to critically appraise the evidence on the impact of
periodontal treatment of cardiovascular diseases (CVDs) biomarkers and outcomes …

The role and function of HDL in patients with diabetes mellitus and the related cardiovascular risk

M Femlak, A Gluba-Brzózka… - Lipids in health and …, 2017 - Springer
Background Diabetes mellitus (DM) is a major public health problem which prevalence is
constantly raising, particularly in low-and middle-income countries. Both diabetes mellitus …

Cardioprotective functions of HDLs1

KA Rye, PJ Barter - Journal of lipid research, 2014 - ASBMB
Multiple human population studies have established the concentration of high density
lipoprotein (HDL) cholesterol as an independent, inverse predictor of the risk of having a …

The emerging role of HDL in glucose metabolism

BG Drew, KA Rye, SJ Duffy, P Barter… - Nature Reviews …, 2012 - nature.com
A low plasma level of HDL cholesterol is an atherosclerotic risk factor; however, emerging
evidence suggests that low HDL levels might also contribute to the pathophysiology of type …