In the two decades since their initial discovery, DNA vaccines technologies have come a
long way. Unfortunately, when applied to human subjects inadequate immunogenicity is still …

Tuberculosis (TB), caused by the intracellular bacterium Mycobacterium tuberculosis (Mtb),
remains a major health threat. A live, attenuated mycobacterium known as Bacille Calmette …

Approximately 2 billion people are infected with M ycobacterium tuberculosis, the etiological
agent of tuberculosis (TB), and an estimated 1.5 million individuals die annually from TB …

Mycobacterium tuberculosis (Mtb) is one of the most life-threatening mycobacterial species
which is increasing the death rate due to emerging multi-drug resistant (MDR) strains …

Mycobacterium tuberculosis (M. tb) infection leads to active tuberculosis (TB), a disease that
kills one human every 18 s. Current therapies available to combat TB include chemotherapy …

Antimicrobial peptides (AMPs) are molecules with a broad-spectrum activity against
bacteria, fungi, protozoa, and viruses. These peptides are widely distributed in insects …

Among the various biological properties presented by Mesenchymal Stem Cells (MSCs),
their ability to control the immune response and fight pathogen infection through the …

Tuberculosis (TB), a disease caused by the human pathogen Mycobacterium tuberculosis,
has recently joined HIV/AIDS as the world's deadliest infectious disease, affecting around …

There is an urgent need for an improved TB vaccine. Vaccine development is hindered by
the lack of immune correlates and uncertain predictive value of preclinical animal models …

Introduction To comprehensively identify and provide an overview of in vivo or clinical
studies of nucleic acids (NA)-based vaccines against TB we included human or animal …