The execution and analysis of complex experiments are challenged by the vast
dimensionality of the underlying parameter spaces. Although an increase in data-acquisition …

Surface gradients of chemistry or morphology represent powerful tools for the high-
throughput investigation of interfacial phenomena in the areas of physics, chemistry …

In order to accelerate tissue-engineering research, a combinatorial approach for
investigating the effect of surface energy on cell response has been developed. Surface …

Thickness is a governing factor in the behavior of films and coatings. To enable the high-
throughput analysis of this parameter in polymer systems, we detail the design and …

The importance of biomaterials has been recognized in biomedical research for over three
decades. Their practical utilization in biomedical applications depends on the appropriate …

Molecular mapping of live biofilms at submicrometer resolution presents a grand challenge.
Here, we present the first chemical mapping results of biofilm extracellular polymeric …

Rational design of bioactive tissue engineered scaffolds for directing bone regeneration in
vivo requires a comprehensive understanding of cell interactions with the immobilized …

Physical and chemical surface or interface properties play key roles in high-tech fields such
as biotechnology, 1 electronics, 2 and photonics 3 by virtue of the various kinds of physical …

Versatile templates for gradient immobilization of biomolecules by click chemistry are easily
generated from reproducible and tunable surface energy gradients. An arginine–glycine …

Gradient surfaces are widely employed in biological studies for protein adsorption and cell
attachment and growth. They also offer great potential in the areas of fluid flow and …