Molecular mechanisms of transgenerational epigenetic inheritance

MH Fitz-James, G Cavalli - Nature Reviews Genetics, 2022 - nature.com
Increasing evidence indicates that non-DNA sequence-based epigenetic information can be
inherited across several generations in organisms ranging from yeast to plants to humans …

The molecular basis of heterochromatin assembly and epigenetic inheritance

SIS Grewal - Molecular cell, 2023 - cell.com
Heterochromatin plays a fundamental role in gene regulation, genome integrity, and
silencing of repetitive DNA elements. Histone modifications are essential for the …

Fungi as mediators linking organisms and ecosystems

M Bahram, T Netherway - FEMS Microbiology Reviews, 2022 - academic.oup.com
Fungi form a major and diverse component of most ecosystems on Earth. They are both
micro and macroorganisms with high and varying functional diversity as well as great …

Epigenetic inheritance and reproductive mode in plants and animals

D Anastasiadi, CJ Venney, L Bernatchez… - Trends in Ecology & …, 2021 - cell.com
Epigenetic inheritance is another piece of the puzzle of nongenetic inheritance, although the
prevalence, sources, persistence, and phenotypic consequences of heritable epigenetic …

[HTML][HTML] Paternal microbiome perturbations impact offspring fitness

A Argaw-Denboba, TSB Schmidt, M Di Giacomo… - Nature, 2024 - nature.com
The gut microbiota operates at the interface of host–environment interactions to influence
human homoeostasis and metabolic networks,,–. Environmental factors that unbalance gut …

Novel antifungals and treatment approaches to tackle resistance and improve outcomes of invasive fungal disease

M Hoenigl, A Arastehfar, MC Arendrup… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Fungal infections are on the rise, driven by a growing population at risk and climate change.
Currently available antifungals include only five classes, and their utility and efficacy in …

Empirical evidence for epigenetic inheritance driving evolutionary adaptation

D Stajic, LET Jansen - Philosophical Transactions of the …, 2021 - royalsocietypublishing.org
The cellular machinery that regulates gene expression can be self-propagated across cell
division cycles and even generations. This renders gene expression states and their …

CHD7 regulates bone-fat balance by suppressing PPAR-γ signaling

C Liu, Q Xiong, Q Li, W Lin, S Jiang, D Zhang… - Nature …, 2022 - nature.com
Chromodomain helicase DNA-binding protein 7 (CHD7), an ATP-dependent eukaryotic
chromatin remodeling enzyme, is essential for the development of organs. The mutation of …

Minimal requirements for the epigenetic inheritance of engineered silent chromatin domains

AH Yuan, D Moazed - … of the National Academy of Sciences, 2024 - National Acad Sciences
Mechanisms enabling genetically identical cells to differentially regulate gene expression
are complex and central to organismal development and evolution. While gene silencing …

The phenomenon of strain degeneration in biotechnologically relevant fungi

C Danner, RL Mach, AR Mach-Aigner - Applied Microbiology and …, 2023 - Springer
Fungi are widely exploited for large-scale production in the biotechnological industry to
produce a diverse range of substances due to their versatility and relative ease of growing …