Summary July 20, 2021 marked the 30th anniversary of the publication of the landmark trial
by the British Medical Research Council showing unequivocally that maternal intake of folic …

Besides aging, a number of non-modifiable lifestyle-related factors, such as smoking,
elevated consumption of caffeine and alcohol, stress, agonist sports, chronic exposure to …

More evidence is available for maternal intake, absorption, distribution, tissue specific
concentrations, and pregnancy outcomes with folic acid (fortification/supplementation) …

Neural tube defects (NTDs) are common birth defects and contribute to life-long disabilities,
high medical care costs, and perinatal and child mortality. This review is a primer on …

Healthy lifestyle behaviors during the preconception period are important to optimize
maternal and child outcomes, including weight. However, the majority of women do not have …

Background Neural tube defects are common birth defects resulting in severe morbidity and
mortality; they can largely be prevented with periconceptional maternal intake of folic acid …

Background A growing body of evidences suggests an association between early exposure
to organophosphates (OPs), organochlorines (OCs), pyrethroids or carbamates and autism …

Background Preconception exposures have been associated with adverse pregnancy, birth
and postpartum outcomes. However, the reports, statements and guidelines of national and …

Background Several preconception exposures have been associated with adverse
pregnancy, birth and postpartum outcomes. However, few studies have investigated …

The study aims to estimate the trends in incidence and mortality of congenital birth defects at
global, regional, and national levels from 1990 to 2019. Annual incident cases, age …