Dysregulation of galectin expression is frequently observed in cancer tissues. Such an
abnormal expression pattern often correlates with aggressiveness and relapse in many …

Although considerable attention has been paid to the role of extracellular galectins in
modulating, positively or negatively, tumor growth and metastasis, we have witnessed a …

Galectins are an evolutionarily ancient and widely expressed family of lectins that have
unique glycan-binding characteristics. They are pleiotropic regulators of key biological …

Metastasis predicts poor prognosis in cancer patients. It has been recognized that specific
tumor microenvironment defines cancer cell metastasis, whereas the underlying …

Galectin-7, a member of the β-galactoside-binding protein family, is primarily expressed in
stratified epithelial cells, including keratinocytes. There is information in the literature …

Background Resistance to apoptosis induced by anti-cancer drugs is a major obstacle for
the treatment of aggressive forms of breast cancer. Galectin-7 (gal-7) was recently shown to …

Galectins are small unglycosylated soluble lectins distributed both inside and outside the
cells. They share a conserved domain for the recognition of carbohydrates (CRD). Although …

Simple Summary Mitochondrial stress responses play a key role in cancer progression.
Tid1, a mitochondrial co-chaperone, has been investigated and may act as a tumor …

Galectins are moving closer to center stage in detecting glycosylation aberration in cancer
cells. Here, we have investigated the expression of galectins in ovarian cancer (OC) and …

Galectin-7 was initially described as a marker of epithelial differentiation expressed in the
stratified epithelium of various tissues. Like other members of the galectin family, its …