The idiopathic generalized epilepsies (IGE) make up a fifth of all epilepsies, but< 1% of
epilepsy research. This skew reflects misperceptions: diagnosis is straightforward …

The central nervous system (CNS) exhibits remarkable adaptability throughout life, enabled
by intricate interactions between neurons and glial cells, in particular, oligodendrocytes …

Typical absence seizures (ASs) are brief periods of lack of consciousness, associated with
2.5–4 Hz spike-wave discharges (SWDs) in the EEG, which are highly prevalent in children …

Approximately 30% of patients with epilepsy are drug-refractory. There is an urgent need to
elucidate the exact pathophysiology of different types of epilepsies and the mechanisms of …

The neocortex controls its own sensory input in part through top-down inhibitory
mechanisms. Descending corticothalamic projections drive GABAergic neurons of the …

Abstract The Endoplasmic Reticulum (ER) is associated with many cellular functions, from
post-transcriptional modifications to the proper folding of proteins, and disruption of these …

Objectives:< p> Review the latest International League Against Epilepsy classification
system for epilepsy.</p>< p> Summarize the typical presentation of childhood absence …

Abstract Objective Approximately 20–30% of epilepsy patients exhibit negative findings on
routine magnetic resonance imaging, and this condition is known as nonlesional epilepsy …

Background Patients with genetic deficiency of the adaptor protein complex 4 (AP-4) exhibit
earlyonset developmental delay, spastic diplegia, intellectual disability, speech impairment …

Background: Recent studies have described unique aspects of default mode network
connectivity in patients with idiopathic generalized epilepsy (IGE). A complete background in …