CRISPR/Cas9 genome editing has gained rapidly increasing attentions in recent years,
however, the translation of this biotechnology into therapy has been hindered by efficient …

RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

Since its discovery, the CRISPR/Cas technology has rapidly become an essential tool in
modern biomedical research. The opportunities to specifically modify and correct genomic …

The CRISPR-Cas system initiated a revolution in genome editing when it was, for the first
time, demonstrated success in the mammalian cells. Today, scientists are able to readily edit …

Current CRISPR-Cas-based nucleic acid sensing methods relying on the preassembled
Cas-crRNA complexes are generally limited to the detection of protospacer-adjacent motif …

Precisely assembled DNA nanostructures are promising candidates for the delivery of
biomolecule-based therapeutics. Herein, we introduce a facile strategy for the construction …

Clustered regularly interspaced short palindromic repeat (CRISPR)/associated protein
(CRISPR/Cas) system is an adaptable immune mechanism used by many bacteria to protect …

As the up-and-comer in the development of RNA nanotechnology, RNA nanomaterials
based on functionalized rolling circle transcription (RCT) have become promising carriers for …

The clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 system is a
gene-editing technology. Nanoparticle delivery systems have attracted attention because of …

The recent progress in harnessing the efficient and precise method of DNA editing provided
by CRISPR/Cas9 is one of the most promising major advances in the field of gene therapy …