The morphogenesis of the C. elegans embryo is largely controlled by the development of the
epidermis, also known as the hypodermis, a single epithelial layer that surrounds the …

The skin of the nematode Caenorhabditis elegans is composed of a simple epidermal
epithelium and overlying cuticle. The skin encloses the animal and plays central roles in …

Temporal profiles of transcript abundance during embryonic development were obtained by
whole-genome expression analysis from precisely staged C. elegans embryos. The result is …

Understanding transdifferentiation—the conversion of one differentiated cell type into
another—is important from both basic science and clinical perspectives. In Caenorhabditis …

The studies of cell fate and lineage specification are fundamental to our understanding of
the development of multicellular organisms. Caenorhabditis elegans has been one of the …

We report here that WASP and Ena/VASP family proteins play overlapping roles in C.
elegans morphogenesis and neuronal cell migration. Specifically, these studies …

We review the application of Caenorhabditis elegans as a model system to understand key
aspects of stem cell biology. The only bona fide stem cells in C. elegans are those of the …

While Caenorhabditis elegans was originally regarded as a model for investigating
determinate developmental programs, landmark studies have subsequently shown that the …

Cells can change identity during normal development, in response to tissue damage or
defined artificial treatments, or during disease processes such as cancer. Strikingly, not only …

There is increasing interest in the use of the free-living nematode Caenorhabditis elegans
as a tool for parasitic nematode research and there are now a number of compelling …