[HTML][HTML] Cytotoxic activity of the genus Ferula (Apiaceae) and its bioactive constituents

M Iranshahi, R Rezaee, MN Najafi… - Avicenna Journal of …, 2018 - ncbi.nlm.nih.gov
Objective: The genus Ferula L. includes perennial flowering plants belonging to the
Apiaceae family. This genus is a rich source of biologically active phytochemicals such as …

In vitro and in vivo experimental models as tools to investigate the efficacy of antineoplastic drugs on urinary bladder cancer

R Arantes-Rodrigues, A Colaco, R Pinto-Leite… - Anticancer …, 2013 - ar.iiarjournals.org
Several drugs have shown in vitro and in vivo pharmacological activity against urinary
bladder cancer. This review aims at compiling the different drugs evaluated in in vitro and in …

Sesquiterpene Coumarin Ethers with Selective Cytotoxic Activities from the Roots of Ferula huber-morathii Peşmen (Apiaceae) and Unequivocal Determination of the …

FM Eruçar, FK Kuran, G Altıparmak Ülbegi, S Özbey… - Pharmaceuticals, 2023 - mdpi.com
Ancient physicians frequently used the resin of Ferula species to treat cancer. Today, some
folkloric recipes used for cancer treatment also contain the resin of Ferula species. The …

Reversal of P-glycoprotein-mediated multidrug resistance in MCF-7/Adr cancer cells by sesquiterpene coumarins

J Kasaian, F Mosaffa, J Behravan, M Masullo… - Fitoterapia, 2015 - Elsevier
In the present study, fifteen sesquiterpene coumarins were isolated and purified from
different Ferula species, and were tested for their MDR reversal properties. Enhancement of …

[HTML][HTML] Antioxidant, cytotoxic and DNA protective properties of Achillea eriophora DC. and Achillea biebersteinii Afan. extracts: A comparative study

M Varasteh-Kojourian, P Abrishamchi… - Avicenna Journal of …, 2017 - ncbi.nlm.nih.gov
Objective: Achillea is a traditional medicinal herb which contains different phenol and
flavonoid compounds that are responsible for Achillea pharmacological effects. We aimed to …

Ferutinin, an apoptosis inducing terpenoid from Ferula ovina

MM Matin, H Nakhaeizadeh, AR Bahrami… - Asian Pacific Journal …, 2014 - koreascience.kr
A current hurdle in cancer management is the intrinsic or acquired resistance of cancer cells
to chemical agents that restricts the efficacy of therapeutic strategies. Accordingly, there is an …

Investigating anticancer properties of the sesquiterpene ferutinin on colon carcinoma cells, in vitro and in vivo

N Arghiani, MM Matin, AR Bahrami, M Iranshahi… - Life sciences, 2014 - Elsevier
Aims In this research, ferutinin was evaluated for its possible cytotoxic and apoptotic
inducing effects in vitro and in vivo. Main methods To determine IC 50 values of ferutinin …

Thymoquinone enhanced the antitumor activity of cisplatin in human bladder cancer 5637 cells in vitro

F Khodadadi, M Khorashadizadeh… - Molecular Biology Reports, 2023 - Springer
Purpose Cisplatin-based chemotherapy is a primary alternative for treating bladder cancer.
But drug resistance and various side effects are the main unsightliness challenges. In …

Scolicidal effectiveness of essential oil from Zataria multiflora and Ferula assafoetida: disparity between phenolic monoterpenes and disulphide compounds

G Kavoosi, AM Purfard - Comparative Clinical Pathology, 2013 - Springer
Hydatidosis in humans and animals is a substantial cause of deaths in many parts of the
world. Surgery and the chemotherapeutic agents are the main treatments for hydatid …

Investigating the cytotoxic and apoptosis inducing effects of monoterpenoid stylosin in vitro

FB Rassouli, MM Matin, M Iranshahi, AR Bahrami - Fitoterapia, 2011 - Elsevier
The aim of this study was to investigate the cytotoxic and anticancer activities of stylosin, a
monoterpene extracted from an edible plant, Ferula ovina, on 5637 and HFF3 cells using …