Best practices on immunomodulators and biologic agents for ulcerative colitis and Crohn's disease in Asia

CJ Ooi, I Hilmi, R Banerjee, SW Chuah… - Journal of …, 2019 - Wiley Online Library
Abstract The Asia–Pacific Working Group on Inflammatory Bowel Disease was established
in Cebu, Philippines, under the auspices of the Asia–Pacific Association of Gastroenterology …

Systematic review and meta‐analysis: efficacy and safety of early biologic treatment in adult and paediatric patients with Crohn's disease

RC Ungaro, S Aggarwal, O Topaloglu… - Alimentary …, 2020 - Wiley Online Library
Background There is an increasing body of evidence showing that earlier use of biologics
improves clinical outcomes in Crohn's disease (CD). Aim To perform a systematic review …

ECCO guidelines on therapeutics in Crohn's disease: medical treatment

H Gordon, S Minozzi, U Kopylov… - Journal of Crohn's …, 2024 - academic.oup.com
Crohn's disease [CD] is a chronic inflammatory bowel disease [IBD] that can result in
progressive bowel damage and disability. 1 CD can affect individuals of any age, from …

Breaking through the therapeutic ceiling: what will it take?

T Raine, S Danese - Gastroenterology, 2022 - Elsevier
Outcomes for patients starting a new treatment for inflammatory bowel disease are
characterized by uncertainty of treatment response. Although it is natural to hope that new …

The future of biosimilars: maximizing benefits across immune-mediated inflammatory diseases

HU Kim, R Alten, L Avedano, A Dignass, F Gomollón… - Drugs, 2020 - Springer
Biologics have transformed the treatment of immune-mediated inflammatory diseases such
as rheumatoid arthritis (RA) and inflammatory bowel disease (IBD). Biosimilars—biologic …

Evolving short-and long-term goals of management of inflammatory bowel diseases: getting it right, making it last

C Le Berre, A Ricciuto, L Peyrin-Biroulet, D Turner - Gastroenterology, 2022 - Elsevier
Short-and long-term treatment targets in inflammatory bowel diseases (IBDs) evolved during
the last decade, shifting from symptom control to endoscopic healing and patient-centered …

Early biologic treatment decreases risk of surgery in Crohn's disease but not in ulcerative colitis: systematic review and meta-analysis

CCY Law, B Tkachuk, S Lieto, N Narula… - Inflammatory bowel …, 2024 - academic.oup.com
Abstract Background and Aims Inflammatory bowel disease (IBD) can lead to long-term
complications that significantly impact patients' quality of life and healthcare resource …

Early initiation of anti-TNF is associated with favourable long-term outcome in Crohn's disease: 10-year-follow-up data from the Swiss IBD cohort study

R Frei, N Fournier, J Zeitz, M Scharl… - Journal of Crohn's …, 2019 - academic.oup.com
Abstract Background and Aims The optimal timing of treatment escalation in Crohn's disease
[CD] remains a challenging issue, and very little is known about its long-term development …

Changing treatment paradigms for the management of inflammatory bowel disease

JP Im, BD Ye, YS Kim, JS Kim - The Korean journal of internal …, 2017 - pmc.ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic and progressive inf lammatory condition of
the gastrointestinal tract causing bowel damage, hospitalizations, surgeries, and disability …

Increased prevalence of anti‐TNF therapy in paediatric inflammatory bowel disease is associated with a decline in surgical resections during childhood

JJ Ashton, F Borca, E Mossotto… - Alimentary …, 2019 - Wiley Online Library
Background Anti‐tumour necrosis factor‐α (anti‐TNF) therapy use has risen in paediatric‐
onset inflammatory bowel disease (PIBD). Whether this has translated into …