The objective of this article is to present a broad review of the role of cardiac electric rotors
and their accompanying spiral waves in the mechanism of cardiac fibrillation. At the outset …

In a normal human life span, the heart beats about 2–3 billion times. Under diseased
conditions, a heart may lose its normal rhythm and degenerate suddenly into much faster …

Aims Reliable defibrillation with reduced energy deposition has long been the focus of
defibrillation research. We studied the efficacy of single shocks of 300 ns duration in …

Background Precise analysis of cardiac spiral wave (SW) dynamics is essential for effective
arrhythmia treatment. Although the phase singularity (PS) point in the spatial phase map has …

Aim In healthy hearts, ventricular gap junctions are mainly composed by connexin43 (Cx43)
and localize in the intercalated disc, enabling appropriate electrical coupling. In diseased …

Objective: Spiral reentry is a recognized cause of tachycardia. Detection and tracking of the
spiral core are essential for understanding the spiral wave dynamics. The core of the spiral …

Background: Recently, an interoperative catheter electrode mapping system, termed ExTRa
Mapping (EXT), was developed for precise diagnosis and effective treatment of non …

BACKGROUND: Moderate global cooling of myocardial tissue was shown to destabilize 2-
dimensional (2-D) reentry and facilitate its termination. OBJECTIVE: This study sought to test …

Aims The aim of this study was to investigate the role of gap junctions in atrial fibrillation (AF)
by analysing the effects of a gap junction enhancer and blocker on AF vulnerability and …

Congestive heart failure (CHF) predisposes to ventricular fibrillation (VF) in association with
electrical remodeling of the ventricle. However, much remains unknown about the rate …