Glutamine (Gln) is found abundantly in the central nervous system (CNS) where it
participates in a variety of metabolic pathways. Its major role in the brain is that of a …

The ubiquitously expressed serum‐and glucocorticoid‐inducible kinase‐1 (SGK1) is
genomically regulated by cell stress (including cell shrinkage) and several hormones …

Abstract Study Objectives: The sleep-deprivation-induced changes in delta power, an
electroencephalographical correlate of sleep need, and brain transcriptome profiles have …

Regulation of renal Na+ transport is essential for controlling blood pressure, as well as Na+
and K+ homeostasis. Aldosterone stimulates Na+ reabsorption by the Na+-Cl− cotransporter …

Target recognition by the ubiquitin system is mediated by E3 ubiquitin ligases. Nedd4 family
members are E3 ligases comprised of a C2 domain, 2–4 WW domains that bind PY motifs …

The outlined recent findings advanced our understanding of the molecular regulation of
SGK1 as well as the role of the kinase in renal physiology and the pathophysiology of renal …

The present brief review highlights the putative role of the serum‐and glucocorticoid‐
inducible‐kinase‐1 (SGK1) in the regulation of neuronal function. SGK1 is genomically …

Ion channels and transporters play a critical role in ion and fluid homeostasis and thus in
normal animal physiology and pathology. Tight regulation of these transmembrane proteins …

Compelling evidence is accumulating indicating a pathophysiological role of the serum-and-
glucocorticoid-inducible-kinase-1 (SGK1) in the development and complications of diabetes …

Colorectal carcinoma is among the most common malignancies. The tumour cells may arise
from mutations in genes encoding proteins involved in the regulation of cell survival and …