Glia are essential for brain functioning during development and in the adult brain. Here, we
discuss the various roles of both microglia and astrocytes, and their interactions during brain …

Microglia are resident macrophages of the central nervous system (CNS), representing 5–
10% of total CNS cells. Recent findings reveal that microglia enter the embryonic brain, take …

Neurons require trophic support during neural circuit formation; however, how the cellular
milieu contributes to neuronal survival remains unclear. We found that layer V cortical …

The nervous system comprises a remarkably diverse and complex network of different cell
types, which must communicate with one another with speed, reliability, and precision. Thus …

Neural stem and progenitor cells have a central role in the development and evolution of the
mammalian neocortex. In this review, we first provide a set of criteria to classify the various …

Microglia are critical nervous system-specific cells influencing brain development,
maintenance of the neural environment, response to injury, and repair. They contribute to …

During vertebrate development, a wide variety of cell types and tissues emerge from a single
fertilized oocyte. One of these tissues, the central nervous system, contains many types of …

Microglial cells are the resident macrophages of the central nervous system (CNS) and are
mainly known for their roles in neuropathologies. However, major recent developments have …

In vertebrates, during an early wave of hematopoiesis in the yolk sac between embryonic
day E7. 0 and E9. 0, cells of mesodermal leaflet addressed to macrophage lineage enter in …

Human cerebral organoids, derived from induced pluripotent stem cells, offer a unique in
vitro research window to the development of the cerebral cortex. However, a key player in …