The multi-partner consortium to expand dementia research in Latin America (ReDLat): driving multicentric research and implementation science

A Ibanez, JS Yokoyama, KL Possin, D Matallana… - Frontiers in …, 2021 - frontiersin.org
Dementia is becoming increasingly prevalent in Latin America, contrasting with stable or
declining rates in North America and Europe. This scenario places unprecedented clinical …

Modern methods of diagnostics and treatment of neurodegenerative diseases and depression

N Shusharina, D Yukhnenko, S Botman, V Sapunov… - Diagnostics, 2023 - mdpi.com
This paper discusses the promising areas of research into machine learning applications for
the prevention and correction of neurodegenerative and depressive disorders. These two …

[HTML][HTML] Interoception primes emotional processing: multimodal evidence from neurodegeneration

PC Salamone, A Legaz, L Sedeño… - Journal of …, 2021 - Soc Neuroscience
Recent frameworks in cognitive neuroscience and behavioral neurology underscore
interoceptive priors as core modulators of negative emotions. However, the field lacks …

The BrainLat project, a multimodal neuroimaging dataset of neurodegeneration from underrepresented backgrounds

P Prado, V Medel, R Gonzalez-Gomez… - Scientific Data, 2023 - nature.com
Abstract The Latin American Brain Health Institute (BrainLat) has released a unique
multimodal neuroimaging dataset of 780 participants from Latin American. The dataset …

Multi-feature computational framework for combined signatures of dementia in underrepresented settings

S Moguilner, A Birba, S Fittipaldi… - Journal of neural …, 2022 - iopscience.iop.org
Objective. The differential diagnosis of behavioral variant frontotemporal dementia (bvFTD)
and Alzheimer's disease (AD) remains challenging in underrepresented, underdiagnosed …

[HTML][HTML] Dynamic brain fluctuations outperform connectivity measures and mirror pathophysiological profiles across dementia subtypes: a multicenter study

S Moguilner, AM García, YS Perl, E Tagliazucchi… - Neuroimage, 2021 - Elsevier
From molecular mechanisms to global brain networks, atypical fluctuations are the hallmark
of neurodegeneration. Yet, traditional fMRI research on resting-state networks (RSNs) has …

Diagnosis of Alzheimer's disease and behavioural variant frontotemporal dementia with machine learning‐aided neuropsychological assessment using feature …

F Garcia‐Gutierrez, A Delgado‐Alvarez… - … journal of geriatric …, 2022 - Wiley Online Library
Background Neuropsychological assessment is considered a valid tool in the diagnosis of
neurodegenerative disorders. However, there is an important overlap in cognitive profiles …

Artificial intelligence for diagnostic and prognostic neuroimaging in dementia: A systematic review

RJ Borchert, T Azevedo, AP Badhwar… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Artificial intelligence (AI) and neuroimaging offer new opportunities for
diagnosis and prognosis of dementia. Methods We systematically reviewed studies …

Biomarkers for dementia in Latin American countries: Gaps and opportunities

MA Parra, P Orellana, T Leon, CG Victoria… - Alzheimer's & …, 2023 - Wiley Online Library
Limited knowledge on dementia biomarkers in Latin American and Caribbean (LAC)
countries remains a serious barrier. Here, we reported a survey to explore the ongoing work …

The Latin America and the Caribbean Consortium on Dementia (LAC-CD): from networking to research to implementation science

A Ibanez, MA Parra, C Butler - Journal of Alzheimer's …, 2021 - content.iospress.com
In comparison with other regions, dementia prevalence in Latin America is growing rapidly,
along with the consequent clinical, social, and economic burden upon patients and their …