Evaluation of acetylcholine, seizure activity and neuropathology following high-dose nerve agent exposure and delayed neuroprotective treatment drugs in freely …
C Acon-Chen, JA Koenig, GR Smith… - Toxicology …, 2016 - Taylor & Francis
Organophosphorus nerve agents such as soman (GD) inhibit acetylcholinesterase,
producing an excess of acetylcholine (ACh), which results in respiratory distress …
producing an excess of acetylcholine (ACh), which results in respiratory distress …
In vivo microdialysis and electroencephalographic activity in freely moving guinea pigs exposed to organophosphorus nerve agents sarin and VX: analysis of …
JC O'Donnell, JH McDonough, TM Shih - Archives of toxicology, 2011 - Springer
Organophosphorus nerve agents such as sarin (GB) and VX irreversibly inhibit
acetylcholinesterase, causing a buildup of acetylcholine (ACh) in synapses and …
acetylcholinesterase, causing a buildup of acetylcholine (ACh) in synapses and …
The effects of repeated low-dose sarin exposure
TM Shih, SW Hulet, JH McDonough - Toxicology and applied …, 2006 - Elsevier
This project assessed the effects of repeated low-dose exposure of guinea pigs to the
organophosphorus nerve agent sarin. Animals were injected once a day, 5 days per week …
organophosphorus nerve agent sarin. Animals were injected once a day, 5 days per week …
Comparison of extracellular striatal acetylcholine and brain seizure activity following acute exposure to the nerve agents cyclosarin and tabun in freely moving guinea …
JC O'Donnell, C Acon-Chen… - Toxicology …, 2010 - Taylor & Francis
Organophosphorus nerve agents like cyclosarin and tabun are potent cholinesterase
inhibitors. The inhibition of acetylcholinesterase, which is responsible for breaking down …
inhibitors. The inhibition of acetylcholinesterase, which is responsible for breaking down …
The tertiary oxime monoisonitrosoacetone penetrates the brain, reactivates inhibited acetylcholinesterase, and reduces mortality and morbidity following lethal sarin …
TM Shih, BL Oyler, BR Capacio, I Koplovitz - Toxicology and Applied …, 2021 - Elsevier
The brain is a critical target for the toxic action of organophosphorus (OP) inhibitors of
acetylcholinesterase (AChE) such as the nerve agent sarin. However, the available oxime …
acetylcholinesterase (AChE) such as the nerve agent sarin. However, the available oxime …
Role of acetylcholine and gabaergic inhibitory transmission in seizure pattern generation in neural networks integrating the neocortex, hippocampus, basal ganglia …
IG Silkis - Neurochemical Journal, 2020 - Springer
We have analyzed the influence of acetylcholine and GABAergic inhibitory transmission on
the functioning of parallel topically organized cortico-basal ganglia–thalamo-cortical neural …
the functioning of parallel topically organized cortico-basal ganglia–thalamo-cortical neural …
Novi pristup analizi oksima dizajniranih za zaštitu središnjeg živčanog sustava pri trovanju organofosfornim spojevima
T Zorbaz - 2018 - repozitorij.pmf.unizg.hr
Sažetak Toksični organofosforni spojevi inhibiraju acetilkolinesterazu (AChE; EC 3.1. 1.7) u
sinapsama perifernog i središnjeg živčanog sustava (SŽS) te uzrokuju smrt ili dugotrajne …
sinapsama perifernog i središnjeg živčanog sustava (SŽS) te uzrokuju smrt ili dugotrajne …
Implantable biosensors for physiologic status monitoring during hemorrhage
CN Kotanen - 2013 - search.proquest.com
Trauma diagnostics and management are major aims of research for implantable
amperometric enzyme biosensor technology. Biosensors are capable of monitoring …
amperometric enzyme biosensor technology. Biosensors are capable of monitoring …
Роль ацетилхолина и ГАМК-торможения в генерации судорожной активности в нейронных сетях, объединяющих новую кору, гиппокамп, базальные ганглии и …
ИГ Силькис - Нейрохимия, 2020 - elibrary.ru
Проведен анализ влияний ацетилхолина и ГАМК-торможения на функционирование
параллельных, топически организованных нейронных цепей новая кора–базальные …
параллельных, топически организованных нейронных цепей новая кора–базальные …
The phamacokinetics of medical countermeasures against nerve agents
S Armstrong - 2014 - eprints.soton.ac.uk
Nerve agents are organophosphorus compounds that irreversibly inhibit
acetylcholinesterase, causing accumulation of the neurotransmitter acetylcholine and this …
acetylcholinesterase, causing accumulation of the neurotransmitter acetylcholine and this …