Antifungal drug resistance: an emergent health threat

A Vitiello, F Ferrara, M Boccellino, A Ponzo, C Cimmino… - Biomedicines, 2023 - mdpi.com
Fungal infections, named mycosis, can cause severe invasive and systemic diseases that
can even lead to death. In recent years, epidemiological data have recorded an increase in …

[HTML][HTML] Clinical practice guideline for the therapeutic drug monitoring of voriconazole in non-Asian and Asian adult patients: consensus review by the Japanese …

Y Takesue, Y Hanai, K Oda, Y Hamada, T Ueda… - Clinical Therapeutics, 2022 - Elsevier
Purpose Voriconazole, an antifungal drug, is metabolized by a cytochrome P450 isozyme.
Increased adverse effects are observed in Asians because of the high rate of poor …

Consensus guidelines for the diagnosis and management of invasive fungal disease due to moulds other than Aspergillus in the haematology/oncology setting, 2021

O Bupha‐Intr, C Butters, G Reynolds… - Internal Medicine …, 2021 - Wiley Online Library
Invasive fungal disease (IFD) due to moulds other than Aspergillus is a significant cause of
mortality in patients with malignancies or post haemopoietic stem cell transplantation. The …

Invasive Aspergillosis and the Impact of Azole-resistance

D Bosetti, D Neofytos - Current Fungal Infection Reports, 2023 - Springer
Purpose of Review IA (invasive aspergillosis) caused by azole-resistant strains has been
associated with higher clinical burden and mortality rates. We review the current …

Invasive aspergillosis after renal transplantation

LSM Sigera, DW Denning - Journal of Fungi, 2023 - mdpi.com
Over 95,000 renal transplantation procedures were completed in 2021. Invasive
aspergillosis (IA) affects about 1 in 250 to 1 in 43 renal transplant recipients. About 50% of …

[HTML][HTML] The battle against fungi: lessons in antifungal stewardship from COVID 19 times

SS Kanj, SF Haddad, JF Meis, PE Verweij… - International journal of …, 2023 - Elsevier
The COVID-19 pandemic has highlighted the detrimental effect of secondary pathogens in
patients with a primary viral insult. In addition to superinfections with bacterial pathogens …

Ten issues to update in nosocomial or hospital-acquired pneumonia: an expert review

FJ Candel, M Salavert, A Estella, M Ferrer… - Journal of Clinical …, 2023 - mdpi.com
Nosocomial pneumonia, or hospital-acquired pneumonia (HAP), and ventilator-associated
pneumonia (VAP) are important health problems worldwide, with both being associated with …

Current and Future Pathways in Aspergillus Diagnosis

R Dobiáš, DA Stevens, V Havlíček - Antibiotics, 2023 - mdpi.com
Aspergillus fumigatus has been designated by the World Health Organization as a critical
priority fungal pathogen. Some commercially available diagnostics for many forms of …

Consensus guidelines for antifungal stewardship, surveillance and infection prevention, 2021

A Khanina, SY Tio, MR Ananda‐Rajah… - Internal medicine …, 2021 - Wiley Online Library
Invasive fungal diseases (IFD) are serious infections associated with high mortality,
particularly in immunocompromised patients. The prescribing of antifungal agents to prevent …

Invasive fungal infections associated with COVID-19

KM Hlaing, LM Monday, M Nucci, SA Nouér… - Journal of Fungi, 2023 - mdpi.com
The COVID-19 pandemic caused> 6 million deaths worldwide, often from respiratory failure.
Complications frequently occurred in hospitalized patients, particularly in the intensive care …