Gut microbiome, prebiotics, intestinal permeability and diabetes complications

M Snelson, C de Pasquale, EI Ekinci… - Best Practice & Research …, 2021 - Elsevier
Diabetes is a metabolic condition. The composition of the gut microbiota is altered in
diabetes with reduced levels of short chain fatty acids (SCFA) producers, notably butyrate …

Relevance of protein fermentation to gut health

K Windey, V De Preter… - Molecular nutrition & food …, 2012 - Wiley Online Library
It is generally accepted that carbohydrate fermentation results in beneficial effects for the
host because of the generation of short chain fatty acids, whereas protein fermentation is …

Resistant starch alters gut microbiome and metabolomic profiles concurrent with amelioration of chronic kidney disease in rats

DA Kieffer, BD Piccolo, ND Vaziri… - American Journal …, 2016 - journals.physiology.org
Patients and animals with chronic kidney disease (CKD) exhibit profound alterations in the
gut environment including shifts in microbial composition, increased fecal pH, and increased …

Dietary fiber effects in chronic kidney disease: a systematic review and meta-analysis of controlled feeding trials

L Chiavaroli, A Mirrahimi, JL Sievenpiper… - European journal of …, 2015 - nature.com
Results: A total of 14 trials involving 143 participants met the eligibility criteria. Dietary fiber
supplementation significantly reduced serum urea and creatinine levels in the primary …

The impact of pre‐and/or probiotics on human colonic metabolism: Does it affect human health?

V De Preter, HM Hamer, K Windey… - Molecular nutrition & …, 2011 - Wiley Online Library
Since many years, the role of the colonic microbiota in maintaining the host's overall health
and well‐being has been recognized. Dietary modulation of the microbiota composition and …

[HTML][HTML] Modulation of the gut microbiota by resistant starch as a treatment of chronic kidney diseases: evidence of efficacy and mechanistic insights

M Snelson, NJ Kellow, MT Coughlan - Advances in nutrition, 2019 - Elsevier
Chronic kidney disease (CKD) has been associated with changes in gut microbial ecology,
or “dysbiosis,” which may contribute to disease progression. Recent studies have focused …

Effect of dietary neutral detergent fiber on ileal digestibility and portal flux of nitrogen and amino acids and on nitrogen utilization in growing pigs

NP Lenis, P Bikker, J Van der Meulen… - Journal of Animal …, 1996 - academic.oup.com
Two experiments were conducted to determine the effects of dietary NDF on apparent ileal
and fecal digestibility and portal flux of nitrogen (N) and amino acids, and on N retention in …

Prebiotic Supplementation of In Vitro Fecal Fermentations Inhibits Proteolysis by Gut Bacteria, and Host Diet Shapes Gut Bacterial Metabolism and Response to …

X Wang, GR Gibson, A Costabile, M Sailer… - Applied and …, 2019 - Am Soc Microbiol
Metabolism of protein by gut bacteria is potentially detrimental due to the production of toxic
metabolites, such as ammonia, amines, p-cresol, and indole. The consumption of prebiotic …

[HTML][HTML] Mice fed a high-fat diet supplemented with resistant starch display marked shifts in the liver metabolome concurrent with altered gut bacteria

DA Kieffer, BD Piccolo, ML Marco, EB Kim… - The Journal of …, 2016 - Elsevier
Background: High-amylose-maize resistant starch type 2 (HAMRS2) is a fermentable dietary
fiber known to alter the gut milieu, including the gut microbiota, which may explain the …

Dietary enrichment of resistant starches or fibers differentially alter the feline fecal microbiome and metabolite profile

AH Lee, AR Jha, S Do, E Scarsella, J Shmalberg… - Animal Microbiome, 2022 - Springer
Background Cats are strict carnivores but possess a complex gastrointestinal (GI) microbial
community that actively ferments dietary substrates that are not digested and reach the …