DNA methylation is an epigenetic mark that has suspected regulatory roles in a broad range
of biological processes and diseases. The technology is now available for studying DNA …

Domestication of livestock species and a long history of migrations, selection and adaptation
have created an enormous variety of breeds. Conservation of these genetic resources relies …

Single-cell transcriptomics offers unprecedented opportunities to infer the ligand–receptor
(LR) interactions underlying cellular networks. We introduce a new, curated LR database …

Ticks transmit more pathogens to humans and animals than any other arthropod. We
describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors …

A detailed understanding of the molecular mechanism of SARS-CoV-2 pathogenesis is still
elusive, and there is a need to address its deadly nature and to design effective …

Abstract SMART (Simple Modular Architecture Research Tool) is an online resource
(http://smart. embl. de/) for the identification and annotation of protein domains and the …

Thousands of mutations are identified yearly. Although many directly affect protein
expression, an increasing proportion of mutations is now believed to influence mRNA …

Many patients suffering from developmental disorders harbor submicroscopic deletions or
duplications that, by affecting the copy number of dosage-sensitive genes or disrupting …

Eukaryotic cells replicate by a complex series of evolutionarily conserved events that are
tightly regulated at defined stages of the cell division cycle. Progression through this cycle …

The immunoglobulin (Ig) superfamily consists of many critical immune regulators, including
the B7 family ligands and receptors. In this study, we identify a novel and structurally distinct …