Proteinaceous nanometer-scale pores are ubiquitous in biology. The canonical ionic
channels (eg, those that transport Na+, K+, Ca 2+, and Cl− across cell membranes) play key …

The unzipping kinetics for lesion-containing DNA duplexes was studied in an α-hemolysin (α-
HL) nanopore. The lesion of focus was the guanine two-electron oxidation product, 8-oxo-7 …

The influence of DNA duplex structural destabilization introduced by a single base-pair
modification was investigated by nanopore measurements. A series of 11 modified base …

The hairpin structure is a common and fundamental secondary structure in macromolecules.
In this work, the process of the translocation of a model polymer chain with a hairpin …

When an electric field is applied to an insulating membrane, movement of charged particles
through a nanopore is induced. The measured ionic current reports on biomolecules …

By applying an electric field to an insulating membrane, movement of charged particles
through a nanopore can be induced. The measured ionic current reports on biomolecules …

Currently, when patients are diagnosed with cancer, they often receive a treatment based on
the type and stage of the tumor. However, different patients may respond to the same …

Hiermit erkläre ich, 1. dass mir die geltende Promotionsordnung der Fakultät für Physik der
Universität Bielefeld bekannt ist. 2. dass ich die vorliegende Dissertation selbst angefertigt …

Nanopores are small (1–100 nm diameter) holes/channels formed in biological membranes
(Fig. 1) or fabricated in synthetic materials (Fig. 2). Permeation of ions and small molecules …

Nanopore sequencing has the potential to become a direct, fast and inexpensive DNA
sequencing technology. The simplest form of nanopore DNA sequencing utilizes the …