Integrating Machine Learning with Multi-Omics Technologies in Geroscience: Towards Personalized Medicine

N Theodorakis, G Feretzakis, L Tzelves… - Journal of Personalized …, 2024 - mdpi.com
Aging is a fundamental biological process characterized by a progressive decline in
physiological functions and an increased susceptibility to diseases. Understanding aging at …

Macrophage migration inhibitor factor (MIF): potential role in cognitive impairment disorders

L Zeng, P Hu, Y Zhang, M Li, S Li, A Luo - Cytokine & Growth Factor …, 2024 - Elsevier
Macrophage migration inhibitory factor (MIF) is a cytokine in the immune system,
participated in both innate and adaptive immune responses. Except from immune cells, MIF …

Investigation of the Circular Transcriptome in Alzheimer's Disease Brain

Y Gao, SM Xu, Y Cheng, K Takenaka, G Lindner… - Journal of Molecular …, 2024 - Springer
Circular RNAs (circRNAs) are a subclass of non-coding RNAs which have demonstrated
potential as biomarkers for Alzheimer's disease (AD). In this study, we conducted a …

[HTML][HTML] Glutamate: Molecular Mechanisms and Signaling Pathway in Alzheimer's Disease, a Potential Therapeutic Target

N Puranik, M Song - Molecules, 2024 - mdpi.com
Gamma-glutamate is an important excitatory neurotransmitter in the central nervous system
(CNS), which plays an important role in transmitting synapses, plasticity, and other brain …

[HTML][HTML] Identifying Hub Genes and miRNAs Associated with Alzheimer's Disease: A Bioinformatics Pathway to Novel Therapeutic Strategies

E Gascón, AC Calvo, N Molina, P Zaragoza, R Osta - Biomolecules, 2024 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder that mainly affects the elderly
population. It is characterized by cognitive impairment and dementia due to abnormal levels …

Apoptosis, Autophagy, and Mitophagy Genes in the CA3 Area in an Ischemic Model of Alzheimer's Disease with 2-Year Survival

R Pluta, A Bogucka-Kocka, J Bogucki… - Journal of …, 2024 - content.iospress.com
Background: Currently, no evidence exists on the expression of apoptosis (CASP3),
autophagy (BECN1), and mitophagy (BNIP3) genes in the CA3 area after ischemia with long …

Electrochemical Acetylcholinesterase Sensors for Anti-Alzheimer's Disease Drug Determination

A Ivanov, R Shamagsumova, M Larina, G Evtugyn - Biosensors, 2024 - mdpi.com
Neurodegenerative diseases and Alzheimer's disease (AD), as one of the most common
causes of dementia, result in progressive losses of cholinergic neurons and a reduction in …

Introduction to Alzheimer's Disease, Biomarkers, and the AI Revolution

B Yingngam - AI-Driven Alzheimer's Disease Detection and …, 2024 - igi-global.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease that results in a
steady decline in cognitive ability and memory function. As society ages, the need for an …

Study on Gamma sensory flicker for Insomnia

Y Liu, X Li, S Liu, T Liang, Y Wu, X Wang… - International Journal of …, 2024 - Taylor & Francis
Objectives Insomnia has been the subject of much systematic research because it is a risk
factor for a variety of diseases. There is some evidence that gamma sensory stimulation …

[HTML][HTML] 阿尔茨海默病circRNA 的差异表达及生物信息学分析

张鑫, 闫林娜, 王梓炫 - Advances in Clinical Medicine, 2024 - hanspub.org
目的: 通过生物信息学方法, 探讨阿尔茨海默病(AD) 患者外周血中差异表达的环状RNA
(circRNA) 的生物学功能. 方法: 通过基因表达综合数据库(GEO) 获取AD 相关的数据集 …