Patients diagnosed with epithelial ovarian cancer (OC) have a 5-year survival rate of 49%.
For early-stage disease, the 5-year survival rate is above 90%. However, advanced-stage …

Liver cancer (hepatocellular carcinoma [HCC]) is a fatal cancer worldwide and often is
detected at an advanced stage when treatment options are very limited. This drives the …

Early-onset colorectal cancer (EOCRC), defined as a diagnosis under age 50, is an
emerging public health burden. As many of these individuals fall outside of screening …

The basic function of the immune system is the protection of the host against infections,
along with the preservation of the individual antigenic identity. The process of self-tolerance …

Background Liquid biopsy testing, especially molecular tumor profiling of circulating tumor
DNA (ctDNA) in cell-free plasma, has received increasing interest in recent years as it …

Early detection of pancreatic cancer has been shown to improve patient survival rates.
However, effective early detection tools to detect pancreatic cancer do not currently exist …

Cell-free DNA (cfDNA), a burgeoning class of molecular biomarkers, has been extensively
studied across a variety of biomedical fields. As a key component of liquid biopsy, cfDNA …

This review summarizes the status of resolving the problem of false positive serologic results
(FPSR) in Brucella serology, compiles our knowledge on the molecular background of the …

This dissertation focused on exploiting the full potential of urine as liquid biopsy for cancer
research. First this dissertations showed that urine is used for many cancer types and can be …

This thesis presents the work carried out from February 2017 to February 2021 at the
Department of Hematology, Aalborg University Hospital, and the Department of Clinical …