In recent years, gene therapy has made remarkable achievements in tumor treatment. In a
successfully cancer gene therapy, a smart gene delivery system is necessary for both …

For the longest time, the field of nucleic acid delivery has remained skeptical whether or not
polycationic drug carrier systems would ever make it into clinical practice. Yet, with the …

Although the concept of selective delivery has been postulated over 100 years ago, no
targeted nanomedicine has been clinically approved so far. Nanoparticles modified with …

Nanoparticle-based delivery systems have contributed to the recent clinical success of RNA
therapeutics, including siRNA and mRNA. RNA delivery using polymers has several distinct …

The co-assembly of ionic-neutral block copolymers with oppositely charged species
produces nanometric colloidal complexes, known, among other names, as complex …

Super-resolution microscopy, or nanoscopy, revolutionized the field of cell biology, enabling
researchers to visualize cellular structures with nanometric resolution, single-molecule …

The characterization of newly synthesized materials is a cornerstone of all chemistry and
nanotechnology laboratories. For this purpose, a wide array of analytical techniques have …

The successful cytosolic delivery of nanoparticles is hampered by their endosomal
entrapment and degradation. To push forward the smart development of nanoparticles we …

Supramolecular assembly of polyphenols and biomacromolecules (proteins and nucleic
acids) has emerged as a versatile and simple strategy to construct nanomaterials with …

Introduction: Cell-penetrating peptides (CPP) offer versatile tools for the field of drug delivery
and development of macromolecular therapeutics. These tools have matured into …