Therapeutic strategies for dystrophin replacement in Duchenne muscular dystrophy

C Happi Mbakam, G Lamothe, JP Tremblay - Frontiers in Medicine, 2022 - frontiersin.org
Duchenne muscular dystrophy (DMD) is an X-linked hereditary disease characterized by
progressive muscle wasting due to modifications in the DMD gene (exon deletions …

[HTML][HTML] Circ-ZNF609 is a circular RNA that can be translated and functions in myogenesis

I Legnini, G Di Timoteo, F Rossi, M Morlando, F Briganti… - Molecular cell, 2017 - cell.com
Circular RNAs (circRNAs) constitute a family of transcripts with unique structures and still
largely unknown functions. Their biogenesis, which proceeds via a back-splicing reaction, is …

Non-coding RNA regulates the myogenesis of skeletal muscle satellite cells, injury repair and diseases

Y Zhao, M Chen, D Lian, Y Li, Y Li, J Wang, S Deng… - Cells, 2019 - mdpi.com
Skeletal muscle myogenesis and injury-induced muscle regeneration contribute to muscle
formation and maintenance. As myogenic stem cells, skeletal muscle satellite cells have the …

A feedforward regulatory loop between HuR and the long noncoding RNA linc-MD1 controls early phases of myogenesis

I Legnini, M Morlando, A Mangiavacchi, A Fatica… - Molecular cell, 2014 - cell.com
The muscle-specific long noncoding RNA linc-MD1 was shown to be expressed during early
phases of muscle differentiation and to trigger the switch to later stages by acting as a …

Early pathogenesis of Duchenne muscular dystrophy modelled in patient-derived human induced pluripotent stem cells

E Shoji, H Sakurai, T Nishino, T Nakahata, T Heike… - Scientific reports, 2015 - nature.com
Duchenne muscular dystrophy (DMD) is a progressive and fatal muscle degenerating
disease caused by a dystrophin deficiency. Effective suppression of the primary pathology …

Deficiency in the nuclear long noncoding RNA Charme causes myogenic defects and heart remodeling in mice

M Ballarino, A Cipriano, R Tita, T Santini… - The EMBO …, 2018 - embopress.org
Myogenesis is a highly regulated process that involves the conversion of progenitor cells
into multinucleated myofibers. Besides proteins and mi RNA s, long noncoding RNA s (lnc …

Circular RNAs in muscle function and disease

S Greco, B Cardinali, G Falcone, F Martelli - International journal of …, 2018 - mdpi.com
Circular RNAs (circRNAs) are a class of RNA produced during pre-mRNA splicing that are
emerging as new members of the gene regulatory network. In addition to being spliced in a …

Non-coding RNAs: Emerging from the discovery to therapeutic applications

B Baptista, M Riscado, JA Queiroz, C Pichon… - Biochemical …, 2021 - Elsevier
The knowledge about non-coding RNAs (ncRNAs) is rapidly increasing with new data
continuously emerging, regarding their diverse types, applications, and roles. Particular …

Novel Long Noncoding RNAs (lncRNAs) in Myogenesis: a miR-31 Overlapping lncRNA Transcript Controls Myoblast Differentiation

M Ballarino, V Cazzella, D D'Andrea… - … and cellular biology, 2015 - Taylor & Francis
Transcriptome analysis allowed the identification of new long noncoding RNAs differentially
expressed during murine myoblast differentiation. These transcripts were classified on the …

Non-coding RNAs in muscle differentiation and musculoskeletal disease

M Ballarino, M Morlando, A Fatica… - The Journal of clinical …, 2016 - Am Soc Clin Investig
RNA is likely to be the most rediscovered macromolecule in biology. Periodically, new non-
canonical functions have been ascribed to RNA, such as the ability to act as a catalytic …