Ethacrynic Acid: A Promising Candidate for Drug Repurposing as an Anticancer Agent
L Yu, H Lee, SB Rho, MK Park, CH Lee - International Journal of …, 2023 - mdpi.com
Ethacrynic acid (ECA) is a diuretic that inhibits Na-K-2Cl cotransporter (NKCC2) present in
the thick ascending loop of Henle and muculo dens and is clinically used for the treatment of …
the thick ascending loop of Henle and muculo dens and is clinically used for the treatment of …
Molecular modeling approaches to address drug-metabolizing enzymes (DMEs) mediated chemoresistance: a review
Resistance against clinically approved anticancer drugs is the main roadblock in cancer
treatment. Drug metabolizing enzymes (DMEs) that are capable of metabolizing a variety of …
treatment. Drug metabolizing enzymes (DMEs) that are capable of metabolizing a variety of …