BACKGROUND Primary ovarian insufficiency (POI) is characterized by marked
heterogeneity, but with a significant genetic contribution. Identifying exact causative genes …

Premature ovarian insufficiency (POI) is one form of female infertility, defined by loss of
ovarian activity before the age of 40 and characterized by amenorrhea (primary or …

Primary ovarian insufficiency (POI) is determined by exhaustion of follicles in the ovaries,
which leads to infertility before the age of 40 years. It is characterized by a strong familial …

Primary ovarian insufficiency (POI) is characterized by a loss of ovarian function before the
age of 40 and account for one major cause of female infertility. POI relevance is continuously …

Rapid effects of steroid hormones were discovered in the early 1950s, but the subject was
dominated in the 1970s by discoveries of estradiol and progesterone stimulating protein …

Premature ovarian failure (POF) is an ovarian defect characterized by the premature
depletion of ovarian follicles before the age of 40 years, representing one major cause of …

Context Primary ovarian insufficiency (POI) affects 1% of women under 40 years of age. POI
is idiopathic in more than 70% of cases. Though many candidate genes have been …

BACKGROUND This retrospective cohort study was to determine the frequency and types of
chromosomal abnormalities in Han Chinese women with well-documented premature …

Background PGRMC1 (progesterone receptor membrane component 1) is a highly
conserved heme binding protein, which is overexpressed especially in hormone receptor …

The progesterone hormone regulates the human menstrual cycle, pregnancy, and
parturition by its action via the different progesterone receptors and signaling pathways in …