Like most solid tumours, the microenvironment of epithelial-derived gastric adenocarcinoma
(GAC) consists of a variety of stromal cell types, including fibroblasts, and neuronal …

Abstract Galectin-3 (Gal-3) plays important roles in cell proliferation, adhesion,
differentiation, angiogenesis and apoptosis in normal and pathologic tissues. Accumulated …

Increasing evidence suggests that platelets play a predominant role in colon and breast
cancer metastasis, but the underlying molecular mechanisms remain elusive. Glycoprotein …

Colorectal cancer (CRC) is one of the most common malignancies worldwide and remains a
major clinical challenge. Periplocin, a major bioactive component of the traditional Chinese …

Fascin actin-bundling protein 1 (FSCN1) is a highly conserved actin-bundling protein that
cross links F-actin microfilaments into tight, parallel bundles. Elevated FSCN1 levels have …

Fascins are actin‐binding proteins that cross‐link filamentous actin into tightly packed
parallel bundles. These bundles are important for the organization and morphology of an …

Micro RNAs are small non-coding RNAs, which regulate fundamental cellular and
developmental processes at the transcriptional and translational level. In breast cancer, miR …

Background Fascin-1 is an actin-bundling protein expressed in many human carcinomas,
although absent from most normal epithelia. Fascin-1 promotes filopodia formation …

Introduction Galectin-9 (Gal-9) induces adhesion and aggregation of certain cell types and
inhibits the metastasis of tumor cells. T-cell immunoglobulin–and mucin domain-3 …

Galectins are an evolutionarily ancient family of glycan-binding proteins (GBPs) and are
found in all animals. Although they were discovered over 30 years ago, ideas about their …