[HTML][HTML] The CRISPR-Cas toolbox and gene editing technologies
G Liu, Q Lin, S Jin, C Gao - Molecular cell, 2022 - cell.com
The emergence of CRISPR-Cas systems has accelerated the development of gene editing
technologies, which are widely used in the life sciences. To improve the performance of …
technologies, which are widely used in the life sciences. To improve the performance of …
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
The development of new CRISPR–Cas genome editing tools continues to drive major
advances in the life sciences. Four classes of CRISPR–Cas-derived genome editing agents …
advances in the life sciences. Four classes of CRISPR–Cas-derived genome editing agents …
Mechanism and applications of CRISPR/Cas-9-mediated genome editing
M Asmamaw, B Zawdie - Biologics: targets and therapy, 2021 - Taylor & Francis
Clustered regularly interspaced short palindromic repeat (CRISPR) and their associated
protein (Cas-9) is the most effective, efficient, and accurate method of genome editing tool in …
protein (Cas-9) is the most effective, efficient, and accurate method of genome editing tool in …
A highly specific CRISPR-Cas12j nuclease enables allele-specific genome editing
Y Wang, T Qi, J Liu, Y Yang, Z Wang, Y Wang… - Science …, 2023 - science.org
The CRISPR-Cas system can treat autosomal dominant diseases by nonhomologous end
joining (NHEJ) gene disruption of mutant alleles. However, many single-nucleotide …
joining (NHEJ) gene disruption of mutant alleles. However, many single-nucleotide …
Precision genome editing in plants: state-of-the-art in CRISPR/Cas9-based genome engineering
N Wada, R Ueta, Y Osakabe, K Osakabe - BMC Plant Biology, 2020 - Springer
Traditionally, generation of new plants with improved or desirable features has relied on
laborious and time-consuming breeding techniques. Genome-editing technologies have led …
laborious and time-consuming breeding techniques. Genome-editing technologies have led …
A compact Cascade–Cas3 system for targeted genome engineering
CRISPR–Cas technologies have enabled programmable gene editing in eukaryotes and
prokaryotes. However, the leading Cas9 and Cas12a enzymes are limited in their ability to …
prokaryotes. However, the leading Cas9 and Cas12a enzymes are limited in their ability to …
CRISPR systems for COVID-19 diagnosis
H Rahimi, M Salehiabar, M Barsbay, M Ghaffarlou… - ACS …, 2021 - ACS Publications
The emergence of the new coronavirus 2019 (COVID-19) was first seen in December 2019,
which has spread rapidly and become a global pandemic. The number of cases of COVID …
which has spread rapidly and become a global pandemic. The number of cases of COVID …
CRISPR-Cas tools and their application in genetic engineering of human stem cells and organoids
CRISPR-Cas technology has revolutionized biological research and holds great therapeutic
potential. Here, we review CRISPR-Cas systems and their latest developments with an …
potential. Here, we review CRISPR-Cas systems and their latest developments with an …
Targeting miRNA by CRISPR/Cas in cancer: advantages and challenges
Clustered regulatory interspaced short palindromic repeats (CRISPR) has changed
biomedical research and provided entirely new models to analyze every aspect of …
biomedical research and provided entirely new models to analyze every aspect of …
Cas11 enables genome engineering in human cells with compact CRISPR-Cas3 systems
Leading CRISPR-Cas technologies employ Cas9 and Cas12 enzymes that generate RNA-
guided dsDNA breaks. Yet, the most abundant microbial adaptive immune systems, Type I …
guided dsDNA breaks. Yet, the most abundant microbial adaptive immune systems, Type I …