[HTML][HTML] Emerging viruses: Cross-species transmission of coronaviruses, filoviruses, henipaviruses, and rotaviruses from bats

J Tian, J Sun, D Li, N Wang, L Wang, C Zhang, X Meng… - Cell Reports, 2022 - cell.com
Emerging infectious diseases, especially if caused by bat-borne viruses, significantly affect
public health and the global economy. There is an urgent need to understand the …

Amantadine disrupts lysosomal gene expression: A hypothesis for COVID19 treatment

SP Smieszek, BP Przychodzen… - International journal of …, 2020 - Elsevier
SARS-coronavirus 2 is the causal agent of the COVID-19 outbreak. SARS-Cov-2 entry into a
cell is dependent upon binding of the viral spike (S) protein to cellular receptor and on …

Accelerated viral dynamics in bat cell lines, with implications for zoonotic emergence

CE Brook, M Boots, K Chandran, AP Dobson… - Elife, 2020 - elifesciences.org
Bats host virulent zoonotic viruses without experiencing disease. A mechanistic
understanding of the impact of bats' virus hosting capacities, including uniquely constitutive …

Molecular determinants of cross-species transmission in emerging viral infections

A Wickenhagen, S van Tol… - … and Molecular Biology …, 2024 - journals.asm.org
Several examples of high-impact cross-species transmission of newly emerging or re-
emerging bat-borne viruses, such as Sudan virus, Nipah virus, and severe acute respiratory …

Determination of the factors responsible for the tropism of SARS-CoV-2-related bat coronaviruses to Rhinolophus bat ACE2

S Fujita, Y Kosugi, I Kimura, K Tokunaga, J Ito… - Journal of …, 2023 - Am Soc Microbiol
Differences in host angiotensin converting enzyme 2 (ACE2) genes may affect the host
range of SARS-CoV-2-related coronaviruses (SC2r-CoVs) and further determine the tropism …

Traits, phylogeny and host cell receptors predict Ebolavirus host status among African mammals

M Sundaram, JP Schmidt, BA Han… - PLOS Neglected …, 2022 - journals.plos.org
We explore how animal host traits, phylogenetic identity and cell receptor sequences relate
to infection status and mortality from ebolaviruses. We gathered exhaustive databases of …

Distinct interferon response in bat and other mammalian cell lines infected with Pteropine orthoreovirus

R Tarigan, T Katta, H Takemae, H Shimoda, K Maeda… - Virus Genes, 2021 - Springer
Bats serve as natural hosts of Pteropine orthoreovirus (PRV), an emerging group of bat-
borne, zoonotic viruses. Bats appear to possess unique innate immune system responses …

Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning

G Lasso, M Grodus, E Valencia, V DeJesus, E Liang… - Cell Host & Microbe, 2025 - cell.com
Evidence suggests that bats are important hosts of filoviruses, yet the specific species
involved remain largely unidentified. Niemann-Pick C1 (NPC1) is an essential entry …

Isolation, characterization, and circulation sphere of a filovirus in fruit bats

B He, T Hu, X Yan, Y Pa, Y Liu, Y Liu… - Proceedings of the …, 2024 - National Acad Sciences
Bats are associated with the circulation of most mammalian filoviruses (FiVs), with
pathogenic ones frequently causing deadly hemorrhagic fevers in Africa. Divergent FiVs …

Ebolavirus evolution and emergence are associated with land use change

CE Lange, TR Barnum, DJ McIver… - Ecological …, 2024 - Wiley Online Library
Anthropogenic land use change facilitates disease emergence by altering the interface
between humans and pathogen reservoirs and is hypothesized to drive pathogen evolution …