A comparison of RAFT and ATRP methods for controlled radical polymerization

NP Truong, GR Jones, KGE Bradford… - Nature Reviews …, 2021 - nature.com
Reversible addition–fragmentation chain-transfer (RAFT) polymerization and atom transfer
radical polymerization (ATRP) are the two most common controlled radical polymerization …

Bioorthogonal chemistry

SL Scinto, DA Bilodeau, R Hincapie, W Lee… - Nature Reviews …, 2021 - nature.com
Bioorthogonal chemistry represents a class of high-yielding chemical reactions that proceed
rapidly and selectively in biological environments without side reactions towards …

Click chemistry strategies for the accelerated synthesis of functional macromolecules

Z Geng, JJ Shin, Y Xi, CJ Hawker - Journal of Polymer Science, 2021 - Wiley Online Library
Click chemistry is one of the most powerful strategies for constructing polymeric soft
materials with precise control over architecture and functionality. In this review, we provide a …

Inverse electron demand Diels–Alder reactions in chemical biology

BL Oliveira, Z Guo, GJL Bernardes - Chemical Society Reviews, 2017 - pubs.rsc.org
The emerging inverse electron demand Diels–Alder (IEDDA) reaction stands out from other
bioorthogonal reactions by virtue of its unmatchable kinetics, excellent orthogonality and …

Intramolecular cross-linking methodologies for the synthesis of polymer nanoparticles

S Mavila, O Eivgi, I Berkovich, NG Lemcoff - Chemical reviews, 2016 - ACS Publications
The advancement of polymer science embraces the invention of molecular constructs that
provide functional applications. As a result, the development of novel methodologies for the …

Inverse electron demand Diels–Alder (iEDDA)-initiated conjugation: a (high) potential click chemistry scheme

AC Knall, C Slugovc - Chemical Society Reviews, 2013 - pubs.rsc.org
Inverse electron demand Diels–Alder reactions (iEDDA) between 1, 2, 4, 5-tetrazines and
olefins have emerged into a state-of-the art concept for the conjugation of biomolecules …

Triazolinediones enable ultrafast and reversible click chemistry for the design of dynamic polymer systems

S Billiet, K De Bruycker, F Driessen, H Goossens… - Nature …, 2014 - nature.com
With its focus on synthetic reactions that are highly specific and reliable,'click'chemistry has
become a valuable tool for many scientific research areas and applications. Combining the …

(Photo-) crosslinkable gelatin derivatives for biofabrication applications

J Van Hoorick, L Tytgat, A Dobos, H Ottevaere… - Acta biomaterialia, 2019 - Elsevier
Over the recent decades gelatin has proven to be very suitable as an extracellular matrix
mimic for biofabrication and tissue engineering applications. However, gelatin is prone to …

Dual pH-/thermo-responsive chitosan-based hydrogels prepared using" click" chemistry for colon-targeted drug delivery applications

HT Hoang, SH Jo, QT Phan, H Park, SH Park… - Carbohydrate …, 2021 - Elsevier
A dual pH-/thermo-responsive hydrogel was designed based on a polyelectrolyte complex
of polyacrylic acid (PAA) and norbornene-functionalized chitosan (CsNb), which was …

The Diels–Alder reaction: a powerful tool for the design of drug delivery systems and biomaterials

M Gregoritza, FP Brandl - European journal of pharmaceutics and …, 2015 - Elsevier
Click reactions have the potential to greatly facilitate the development of drug delivery
systems and biomaterials. These reactions proceed under mild conditions, give high yields …