Despite its effectiveness in controlling plasma viremia, antiretroviral therapy (ART) cannot
target proviral DNA, which remains an obstacle to HIV-1 eradication. When treatment is …

HIV‐1 transmembrane protein gp41 plays a crucial role by forming a stable six‐helix bundle
during HIV entry. Due to highly conserved sequence of gp41, the development of an …

Background: HIV-1 drug resistance poses a major threat to the success of antiretroviral
therapy. The high costs of available HIV drug resistance assays prohibit their routine usage …

HIV-1 belongs to the family of Retroviridae and to the genus of Lentivirus. Its high mutation
and recombination rates and high cell turnover result in high levels of genetic diversity. HIV …

Several studies have reported that amyloid fibrils in human semen formed from a naturally
occurring peptide fragment of prostatic acidic phosphatase (PAP248-286), known as semen …

Given the costliness of HIV drug therapy research, it is important not only to maximize true
positive rate (TPR) by identifying which genetic markers are related to drug resistance, but …

HIV‐1 genetic diversity results into the development of widespread drug‐resistant mutations
(DRMs) for the first‐line retroviral therapy. Nevertheless, few studies have investigated the …

Currently, the world is battling the threat of microbial resistance to existing antimicrobial
agents, resulting in overwhelming public health challenges. Response to antimicrobial …

Background Pregnant women and children living with HIV in Kenya achieve viral
suppression (VS) at lower rates than other adults. While many factors contribute to these low …

Background: HIV-1 drug resistance poses a major threat to the success of antiretroviral
therapy. The high costs of available HIV drug resistance assays prohibit their routine usage …