Photodynamic efficiency: from molecular photochemistry to cell death

IOL Bacellar, TM Tsubone, C Pavani… - International journal of …, 2015 - mdpi.com
Photodynamic therapy (PDT) is a clinical modality used to treat cancer and infectious
diseases. The main agent is the photosensitizer (PS), which is excited by light and converted …

Nonporous silica nanoparticles for nanomedicine application

L Tang, J Cheng - Nano today, 2013 - Elsevier
Nanomedicine, the use of nanotechnology for biomedical applications, has potential to
change the landscape of the diagnosis and therapy of many diseases. In the past several …

[HTML][HTML] Hollow microneedle assisted intradermal delivery of hypericin lipid nanocapsules with light enabled photodynamic therapy against skin cancer

H Abd-El-Azim, IA Tekko, A Ali, A Ramadan… - Journal of Controlled …, 2022 - Elsevier
Photodynamic therapy (PDT) to manage non-melanoma skin cancers has garnered great
attention over the past few years. Hypericin (Hy) is a potent lipid-soluble photosensitiser with …

In Vivo Targeted Deep-Tissue Photodynamic Therapy Based on Near-Infrared Light Triggered Upconversion Nanoconstruct

S Cui, D Yin, Y Chen, Y Di, H Chen, Y Ma, S Achilefu… - ACS …, 2013 - ACS Publications
Two major challenges of current photodynamic therapy (PDT) are the limited tissue
penetration of excitation light and poor tumor-selectivity of the photosensitizer (PS). To …

[HTML][HTML] Nanomaterials formulations for photothermal and photodynamic therapy of cancer

ES Shibu, M Hamada, N Murase, V Biju - Journal of Photochemistry and …, 2013 - Elsevier
Nanomaterials with well-defined size, shape, composition, and surface functionalities offer
multimodal and multifunctional platforms for various bioanalytical, bioimaging, and …

Tuning photosensitized singlet oxygen generation efficiency of novel aza-BODIPY dyes

N Adarsh, RR Avirah, D Ramaiah - Organic letters, 2010 - ACS Publications
Novel aza-BODIPY derivatives substituted with heavy atoms such as bromine and iodine
were synthesized, and their triplet and singlet oxygen generation efficiencies have been …

Sunlight-triggered nanoparticle synergy: teamwork of reactive oxygen species and nitric oxide released from mesoporous organosilica with advanced antibacterial …

J Gehring, B Trepka, N Klinkenberg… - Journal of the …, 2016 - ACS Publications
Colonization of surfaces by microorganisms is an urging problem. In combination with the
increasing antibiotic resistance of pathogenic bacteria, severe infections are reported more …

Silica-based nanoparticles for photodynamic therapy applications

P Couleaud, V Morosini, C Frochot, S Richeter… - Nanoscale, 2010 - pubs.rsc.org
Silica-based nanoparticles for applications in photodynamic therapy (PDT) have emerged
as a promising field for the treatment of cancer. In this review, based on the pathway the …

Hematoporphyrin photosensitizer-linked carbon quantum dots for photodynamic therapy of cancer cells

G Murali, B Kwon, H Kang, JKR Modigunta… - ACS Applied Nano …, 2022 - ACS Publications
The direct use of conventional photosensitizers in photodynamic therapy (PDT) of cancer
cells has been thwarted by their low solubility, poor photostability, and aggregation …

Controllable Drug Release and Simultaneously Carrier Decomposition of SiO2-Drug Composite Nanoparticles

S Zhang, Z Chu, C Yin, C Zhang, G Lin… - Journal of the American …, 2013 - ACS Publications
Drug release simultaneously with carrier decomposition has been demonstrated in SiO2-
drug composite nanoparticles. By creating a radial drug concentration gradient in the …