Regulation of membrane protein structure and function by their lipid nano-environment
I Levental, E Lyman - Nature Reviews Molecular Cell Biology, 2023 - nature.com
Transmembrane proteins comprise~ 30% of the mammalian proteome, mediating
metabolism, signalling, transport and many other functions required for cellular life. The …
metabolism, signalling, transport and many other functions required for cellular life. The …
Lipid–protein interactions in plasma membrane organization and function
Lipid–protein interactions in cells are involved in various biological processes, including
metabolism, trafficking, signaling, host–pathogen interactions, and transmembrane …
metabolism, trafficking, signaling, host–pathogen interactions, and transmembrane …
PyLipID: a python package for analysis of protein–lipid interactions from molecular dynamics simulations
Lipids play important modulatory and structural roles for membrane proteins. Molecular
dynamics simulations are frequently used to provide insights into the nature of these protein …
dynamics simulations are frequently used to provide insights into the nature of these protein …
Identification and assessment of cardiolipin interactions with E. coli inner membrane proteins
Integral membrane proteins are localized and/or regulated by lipids present in the
surrounding bilayer. While bacteria have relatively simple membranes, there is ample …
surrounding bilayer. While bacteria have relatively simple membranes, there is ample …
Allosteric modulation of ghrelin receptor signaling by lipids
M Damian, M Louet, AAS Gomes, C M'kadmi… - Nature …, 2021 - nature.com
The membrane is an integral component of the G protein-coupled receptor signaling
machinery. Here we demonstrate that lipids regulate the signaling efficacy and selectivity of …
machinery. Here we demonstrate that lipids regulate the signaling efficacy and selectivity of …
Specific interactions of peripheral membrane proteins with lipids: what can molecular simulations show us?
AH Larsen, LH John, MSP Sansom… - Bioscience …, 2022 - portlandpress.com
Peripheral membrane proteins (PMPs) can reversibly and specifically bind to biological
membranes to carry out functions such as cell signalling, enzymatic activity, or membrane …
membranes to carry out functions such as cell signalling, enzymatic activity, or membrane …
Supramolecular organisation and dynamics of mannosylated phosphatidylinositol lipids in the mycobacterial plasma membrane
661-Pos Supramolecular organisation and dynamics of mannosylated phosphatidylinositol
lipids in the mycobacterial plasma membrane Chelsea M. Brown1, Robin A. Corey2, Ya …
lipids in the mycobacterial plasma membrane Chelsea M. Brown1, Robin A. Corey2, Ya …
[HTML][HTML] Membrane specificity of the human cholesterol transfer protein STARD4
R Talandashti, L van Ek, C Gehin, D Xue… - Journal of Molecular …, 2024 - Elsevier
STARD4 regulates cholesterol homeostasis by transferring cholesterol between the plasma
membrane and endoplasmic reticulum. The STARD4 structure features a helix-grip fold …
membrane and endoplasmic reticulum. The STARD4 structure features a helix-grip fold …
Insights into lipid-protein interactions from computer simulations
Lipid-protein interactions play an important direct role in the function of many membrane
proteins. We argue they are key players in membrane structure, modulate membrane …
proteins. We argue they are key players in membrane structure, modulate membrane …
Dissecting peripheral protein-membrane interfaces
Peripheral membrane proteins (PMPs) include a wide variety of proteins that have in
common to bind transiently to the chemically complex interfacial region of membranes …
common to bind transiently to the chemically complex interfacial region of membranes …