Chronic cough is globally prevalent across all age groups. This disorder is challenging to
treat because many pulmonary and extrapulmonary conditions can present with chronic …

Mast cells have crucial roles in allergic and other inflammatory diseases. Preclinical
approaches provide circumstantial evidence for mast cell involvement in many diseases, but …

These guidelines incorporate the recent advances in chronic cough pathophysiology,
diagnosis and treatment. The concept of cough hypersensitivity has allowed an umbrella …

Background The IL-33/ST2 pathway is linked with asthma susceptibility. Inhaled allergens,
pollutants, and respiratory viruses, which trigger asthma exacerbations, induce release of IL …

Oxidative stress is defined as the imbalance between reactive oxygen species (ROS)
production and the endogenous antioxidant defense system, leading to cellular damage …

Asthma is a chronic disease of the airways, which affects more than 350 million people
worldwide. It is the most common chronic disease in children, affecting at least 30 million …

Asthma and chronic obstructive pulmonary disease (COPD) both cause airway obstruction
and are associated with chronic inflammation of the airways. However, the nature and sites …

Asthma is a common disease that affects 300 million people worldwide. Given the large
number of eosinophils in the airways of people with mild asthma, and verified by data from …

Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society …

Mast cells (MCs) play a pathobiologic role in type 2 (T2) allergic inflammatory diseases of
the airway, including asthma and chronic rhinosinusitis with nasal polyposis (CRSwNP) …