BACKGROUND Innate lymphoid cells (ILCs) are a growing family of immune cells that mirror
the phenotypes and functions of T cells. Natural killer (NK) cells can be considered the …

The nuclear receptors REV-ERB (consisting of REV-ERBα and REV-ERBβ) and retinoic acid
receptor-related orphan receptors (RORs; consisting of RORα, RORβ and RORγ) are …

Osteoarthritis—the most common form of age-related degenerative whole-joint disease—is
primarily characterized by cartilage destruction, as well as by synovial inflammation …

Circadian rhythms occur in almost all species and control vital aspects of our physiology,
from sleeping and waking to neurotransmitter secretion and cellular metabolism …

Circadian rhythms are∼ 24-h oscillations in behavior and physiology, which are internally
generated and function to anticipate the environmental changes associated with the solar …

Nuocytes are essential in innate type 2 immunity and contribute to the exacerbation of
asthma responses. Here we found that nuocytes arose in the bone marrow and …

T cell functional differentiation is mediated by lineage-specific transcription factors. T helper
17 (Th17) has been recently identified as a distinct Th lineage mediating tissue …

Innate lymphoid cells (ILCs) are a recently described family of lymphoid effector cells that
have important roles in immune defence, inflammation and tissue remodelling. It has been …

The discovery that expansion of unstable repeats can cause a variety of neurological
disorders has changed the landscape of disease-oriented research for several forms of …

The mammalian circadian clock plays an integral role in timing rhythmic physiology and
behavior, such as locomotor activity, with anticipated daily environmental changes. The …