Beyond the hippocampus and the SVZ: adult neurogenesis throughout the brain

MP Jurkowski, L Bettio, E K. Woo, A Patten… - Frontiers in cellular …, 2020 - frontiersin.org
Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …

Clinical trials of stem cell therapy for cerebral ischemic stroke

M Kawabori, H Shichinohe, S Kuroda… - International Journal of …, 2020 - mdpi.com
Despite recent developments in innovative treatment strategies, stroke remains one of the
leading causes of death and disability worldwide. Stem cell therapy is currently attracting …

Neuroinflammation as a target for treatment of stroke using mesenchymal stem cells and extracellular vesicles

S Dabrowska, A Andrzejewska, B Lukomska… - Journal of …, 2019 - Springer
Ischemic stroke is the third cause of death in the developed countries and the main reason
of severe disability. Brain ischemia leads to the production of damage-associated molecular …

Intracerebral implantation of human neural stem cells and motor recovery after stroke: multicentre prospective single-arm study (PISCES-2)

KW Muir, D Bulters, M Willmot, N Sprigg… - Journal of Neurology …, 2020 - jnnp.bmj.com
Background Human neural stem cell implantation may offer improved recovery from stroke.
We investigated the feasibility of intracerebral implantation of the allogeneic human neural …

Therapeutic applications of mesenchymal stromal cells: paracrine effects and potential improvements

J Doorn, G Moll, K Le Blanc… - … Engineering Part B …, 2012 - liebertpub.com
Among the various types of cell-to-cell signaling, paracrine signaling comprises those
signals that are transmitted over short distances between different cell types. In the human …

Stem cell transplantation therapy and neurological disorders: current status and future perspectives

MM Rahman, MR Islam, MT Islam, M Harun-Or-Rashid… - Biology, 2022 - mdpi.com
Simple Summary This review highlights the scope of available treatment options for
neurological diseases, especially stem cell transplantation therapy, which provides new …

Mesenchymal stem cell therapy for ischemic stroke: a look into treatment mechanism and therapeutic potential

J Li, Q Zhang, W Wang, F Lin, S Wang, J Zhao - Journal of neurology, 2021 - Springer
Stroke, a global disease with a high disability rate, has limited options for functional
rehabilitation and results in an adverse impact on patients' lives. In recent years …

Adult stem cells for regenerative therapy

N Gurusamy, A Alsayari, S Rajasingh… - Progress in molecular …, 2018 - Elsevier
Cell therapy has been identified as an effective method to regenerate damaged tissue. Adult
stem cells, also known as somatic stem cells or resident stem cells, are a rare population of …

[HTML][HTML] Potential of stem cell-based therapy for ischemic stroke

HE Marei, A Hasan - Frontiers in neurology, 2018 - frontiersin.org
Ischemic stroke is one of the major health problems worldwide. The only FDA approved anti-
thrombotic drug for acute ischemic stroke is the tissue plasminogen activator. Several …

Stem cell transplantation therapy for multifaceted therapeutic benefits after stroke

L Wei, ZZ Wei, MQ Jiang, O Mohamad, SP Yu - Progress in neurobiology, 2017 - Elsevier
One of the exciting advances in modern medicine and life science is cell-based
neurovascular regeneration of damaged brain tissues and repair of neuronal structures. The …