Spin hyperpolarization in modern magnetic resonance

J Eills, D Budker, S Cavagnero, EY Chekmenev… - Chemical …, 2023 - ACS Publications
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …

[HTML][HTML] Solid-state NMR spectroscopy in pharmaceutical sciences

M Li, W Xu, Y Su - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Solid-state NMR (ssNMR) spectroscopy analyzes a wide range of pharmaceutical materials
in a non-disruptive and non-invasive manner. The obtained molecular properties at …

Atomic-level structure determination of amorphous molecular solids by NMR

M Cordova, P Moutzouri, SO Nilsson Lill… - Nature …, 2023 - nature.com
Abstract Structure determination of amorphous materials remains challenging, owing to the
disorder inherent to these materials. Nuclear magnetic resonance (NMR) powder …

Solid-state NMR spectroscopy

B Reif, SE Ashbrook, L Emsley, M Hong - Nature Reviews Methods …, 2021 - nature.com
Solid-state nuclear magnetic resonance (NMR) spectroscopy is an atomic-level method to
determine the chemical structure, 3D structure and dynamics of solids and semi-solids. This …

Recent developments in MAS DNP-NMR of materials

AGM Rankin, J Trébosc, F Pourpoint… - Solid State Nuclear …, 2019 - Elsevier
Solid-state NMR spectroscopy is a powerful technique for the characterization of the atomic-
level structure and dynamics of materials. Nevertheless, the use of this technique is often …

Dynamic nuclear polarization solid-state NMR spectroscopy for materials research

IB Moroz, M Leskes - Annual Review of Materials Research, 2022 - annualreviews.org
Solid-state nuclear magnetic resonance (NMR) spectroscopy has increasingly been used for
materials characterization as it enables selective detection of elements of interest, as well as …

A machine learning model of chemical shifts for chemically and structurally diverse molecular solids

M Cordova, EA Engel, A Stefaniuk… - The Journal of …, 2022 - ACS Publications
Nuclear magnetic resonance (NMR) chemical shifts are a direct probe of local atomic
environments and can be used to determine the structure of solid materials. However, the …

Molecular interactions in posaconazole amorphous solid dispersions from two-dimensional solid-state NMR spectroscopy

X Lu, C Huang, MB Lowinger, F Yang, W Xu… - Molecular …, 2019 - ACS Publications
Molecular interactions between the active pharmaceutical ingredient and polymer have
potentially substantial impacts on the physical stability of amorphous solid dispersions …

DNP‐enhanced solid‐state NMR spectroscopy of active pharmaceutical ingredients

L Zhao, AC Pinon, L Emsley… - Magnetic Resonance in …, 2018 - Wiley Online Library
Solid‐state NMR spectroscopy has become a valuable tool for the characterization of both
pure and formulated active pharmaceutical ingredients (APIs). However, NMR generally …

Characterization of pharmaceutical cocrystals and salts by dynamic nuclear polarization-enhanced solid-state NMR spectroscopy

L Zhao, MP Hanrahan, P Chakravarty… - Crystal Growth & …, 2018 - ACS Publications
Multicomponent solids such as cocrystals have emerged as a way to control and engineer
the stability, solubility, and manufacturability of solid active pharmaceutical ingredients …