Melanoma is a life-threatening malignancy with poor prognosis and a relatively high burden
of mortality in advanced stages. The efficacy of current available therapeutic strategies is …

Skin cancer is, at present, the most common type of malignancy in the Caucasian
population. Its incidence has increased rapidly in the last decade for both melanoma and …

Therapy of melanoma patients harboring activating mutations in the BRAF (V-raf murine
sarcoma viral oncogene homolog B1) oncogene with a combination of BRAF and MEK …

Tumour metastasis is a multistep process. Melanoma is a highly aggressive cancer and
metastasis accounts for the majority of patient deaths. microRNAs (miRNAs) are non-coding …

Melanoma is the less common but the most malignant skin cancer. Since the survival rate of
melanoma metastasis is about 10–15%, many different studies have been carried out in …

Proteins, RNAs and viruses can be spread through exosomes, therefore transport utilizing
these nanovesicles is of the great interest. MiRNAs are common exosomal constituents …

Background: Our previous findings showed that miR-33 expressed abnormally in clinical
specimens of melanoma, but the exact molecular mechanism has not been elucidated …

Determinants of invasion and metastasis in cancer remain of great interest to define. Here,
we report the definition of miR-339-3p as a novel tumor suppressive microRNA that blocks …

In metastatic melanoma, it is vital to identify and validate biomarkers of prognosis. Previous
studies have systematically evaluated protein biomarkers or mRNA-based expression …

In patients with metastatic melanoma, the identification and validation of accurate prognostic
biomarkers will assist rational treatment planning. Studies based on “‐omics” technologies …