Terpenoids from the medicinal mushroom Antrodia camphorata: Chemistry and medicinal potential

Y Kuang, B Li, Z Wang, X Qiao, M Ye - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to February 2020 Antrodia camphorata is a medicinal mushroom endemic to
Taiwan for the treatment of intoxication, liver injury, cancer, and inflammation. Owing to its …

Targeting PI3K/Akt signaling in prostate cancer therapy

M Hashemi, A Taheriazam, P Daneii… - Journal of Cell …, 2023 - Springer
Urological cancers have obtained much attention in recent years due to their mortality and
morbidity. The most common and malignant tumor of urological cancers is prostate cancer …

Molecular panorama of therapy resistance in prostate cancer: a pre-clinical and bioinformatics analysis for clinical translation

M Ashrafizadeh, W Zhang, Y Tian, G Sethi… - Cancer and Metastasis …, 2024 - Springer
Prostate cancer (PCa) is a malignant disorder of prostate gland being asymptomatic in early
stages and high metastatic potential in advanced stages. The chemotherapy and surgical …

Helium/argon-generated cold atmospheric plasma facilitates cutaneous wound healing

BS Lou, JH Hsieh, CM Chen, CW Hou… - … in bioengineering and …, 2020 - frontiersin.org
Cold atmospheric plasma jet (CAPJ) or non-thermal plasma jet has been employed in
various biomedical applications based on their functions in bactericidal activity and wound …

PM2.5 impairs macrophage functions to exacerbate pneumococcus-induced pulmonary pathogenesis

YW Chen, MZ Huang, CL Chen, CY Kuo… - Particle and fibre …, 2020 - Springer
Background Pneumococcus is one of the most common human airway pathogens that
causes life-threatening infections. Ambient fine particulate matter (PM) with aerodynamic …

Multiomics identification of potential targets for Alzheimer disease and antrocin as a therapeutic candidate

ATH Wu, B Lawal, L Wei, YT Wen, DTW Tzeng, WC Lo - Pharmaceutics, 2021 - mdpi.com
Alzheimer's disease (AD) is the most frequent cause of neurodegenerative dementia and
affects nearly 50 million people worldwide. Early stage diagnosis of AD is challenging, and …

The Biosynthetic Gene Cluster of Mushroom‐Derived Antrocin Encodes Two Dual‐Functional Haloacid Dehalogenase‐like Terpene Cyclases

TH Chen, CT Chen, CF Lee, RJ Huang… - Angewandte Chemie …, 2023 - Wiley Online Library
Antrocin (1), produced by the medicinal mushroom Antrodia cinnamomea, is a potent
antiproliferative compound. The biosynthetic gene cluster of 1 was identified, and the …

MiR-223-3p targets FOXO3a to inhibit radiosensitivity in prostate cancer by activating glycolysis

K Zhou, Y Wei, X Li, X Yang - Life Sciences, 2021 - Elsevier
Aims The incidence and detection rate of prostate cancer in China have been increasing in
recent years. Radiotherapy is the ideal treatment for non-metastatic prostate cancer (PCa) …

PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer

S Luszczak, C Kumar, VK Sathyadevan… - Signal transduction and …, 2020 - nature.com
PIM kinases have been shown to play a role in prostate cancer development and
progression, as well as in some of the hallmarks of cancer, especially proliferation and …

Drivers of radioresistance in prostate cancer

L King, N Bernaitis, D Christie… - Journal of Clinical …, 2022 - mdpi.com
Prostate cancer (PCa) is the second most commonly diagnosed cancer worldwide.
Radiotherapy remains one of the first-line treatments in localised disease and may be used …