Genetic approaches to addiction: genes and alcohol

F Ducci, D Goldman - Addiction, 2008 - Wiley Online Library
Aims Alcoholism is a chronic relapsing disorder with an enormous societal impact.
Understanding the genetic basis of alcoholism is crucial to characterize individuals' risk and …

Genetics and alcoholism

HJ Edenberg, T Foroud - Nature reviews Gastroenterology & …, 2013 - nature.com
Alcohol is widely consumed; however, excessive use creates serious physical,
psychological and social problems and contributes to the pathogenesis of many diseases …

Genome-wide association study of alcohol dependence

J Treutlein, S Cichon, M Ridinger… - Archives of general …, 2009 - jamanetwork.com
Context Alcohol dependence is a serious and common public health problem. It is well
established that genetic factors play a major role in the development of this disorder …

A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications

AC Heath, JB Whitfield, NG Martin, ML Pergadia… - Biological …, 2011 - Elsevier
BACKGROUND: Given moderately strong genetic contributions to variation in alcoholism
and heaviness of drinking (50% to 60% heritability) with high correlation of genetic …

[图书][B] The science of addiction: From neurobiology to treatment

CK Erickson - 2018 - books.google.com
An updated and expanded edition on the roles that brain function and genetics play in
addiction. Over the past 10 years, neurobiologic and genetic research has provided an …

Genome‐wide association study of alcohol use disorder identification test (AUDIT) scores in 20 328 research participants of European ancestry

S Sanchez‐Roige, P Fontanillas, SL Elson… - Addiction …, 2019 - Wiley Online Library
Genetic factors contribute to the risk for developing alcohol use disorder (AUD). In
collaboration with the genetics company 23andMe, Inc., we performed a genome‐wide …

The genetics of alcohol dependence

DM Dick, LJ Bierut - Current psychiatry reports, 2006 - Springer
Alcohol dependence is a common, complex disorder, which affects millions of people
worldwide and causes considerable burden in terms of interpersonal and societal costs …

[HTML][HTML] The genetics of alcohol and other drug dependence

DM Dick, A Agrawal - Alcohol Research & Health, 2008 - ncbi.nlm.nih.gov
Alcohol dependence and dependence on other drugs frequently co-occur, and strong
evidence suggests that both disorders are, at least in part, influenced by genetic factors …

Towards understanding the schizophrenia code: an expanded convergent functional genomics approach

H Le‐Niculescu, Y Balaraman, S Patel… - American Journal of …, 2007 - Wiley Online Library
Identifying genes for schizophrenia through classical genetic approaches has proven
arduous. Here, we present a comprehensive convergent analysis that translationally …

The genetics of alcohol dependence

M Rietschel, J Treutlein - Annals of the New York Academy of …, 2013 - Wiley Online Library
Alcohol consumption dates back to the Neolithic period, and alcohol dependence
contributes substantially to the current global burden of disease. Despite this, optimal …