Patients with advanced or recurrent cervical cancer have poor prognosis, and their 1-year
survival is only 10%–20%. Chemotherapy is considered as the standard treatment for …

Cervical cancer (CC) caused by human papillomavirus (HPV) is one of the largest causes of
malignancies in women worldwide. Cisplatin is one of the widely used drugs for the …

Purpose: Resistance to cisplatin-based chemotherapy is a major obstacle to bladder cancer
treatment. We aimed to identify microRNAs (miRNA) that are dysregulated in cisplatin …

Ovarian cancer has a poor overall survival that is partly caused by resistance to drugs such
as cisplatin. Resistance can be acquired as a result of changes to the tumour or due to …

Background: Cancer resistance to chemotherapy is closely associated with changes in
transporter systems. In this study, we investigated the possible regulation of 1 copper ion …

Oxidative stress was predominantly involved in the pathogenesis of acute kidney injury
(AKI). Recent studies had reported the protective role of specific microRNAs (miRNAs) …

Mitochondria play an important role in the initiation of apoptosis. However, whether cisplatin
can induce apoptosis by initiating a mitochondrial fission pathway and the mechanism …

Gynecologic cancer is one of the main causes of death in women. In this type of cancer,
several molecules (oncogenes or tumor suppressor genes) contribute to the tumorigenic …

Introduction Cisplatin is a chemotherapy drug that has been used to treat a number of
cancers for decades, and is still one of the most commonly used anti-cancer agents …

Background Resistance to platinum-based chemotherapy remains a great challenge for
ovarian cancer treatment. The human let-7 family contains 13 members located on nine …