A comprehensive review on process and engineering aspects of pharmaceutical wet granulation

P Suresh, I Sreedhar, R Vaidhiswaran… - Chemical Engineering …, 2017 - Elsevier
Wet granulation is a very important unit operation that finds applications in many industries
mainly pharmaceutical and chemical industries. Various granulation technologies in batch …

Recent trends and future perspective of pharmaceutical wet granulation for better process understanding and product development

P Thapa, J Tripathi, SH Jeong - Powder Technology, 2019 - Elsevier
Current trends in pharmaceutical wet granulation have been shifted from traditional
approach to systematic and modern approaches, enabling the production of highly …

Impact of different dry and wet granulation techniques on granule and tablet properties: a comparative study

OR Arndt, R Baggio, AK Adam, J Harting… - Journal of …, 2018 - Elsevier
Four granulation techniques were compared evaluating their impact on granule properties
and the tablet tensile strength. A common formulation was chosen to be processed with both …

Manufacture and characterization of carbonated lightweight aggregates from waste paper fly ash

B Bouzar, Y Mamindy-Pajany - Powder Technology, 2022 - Elsevier
The combustion of biomass and waste paper sludge in a fluidized bed is ecologically
profitable. However, a large amount of by-product with high hydraulic reactivity is produced …

Mechanistic basis for the effects of process parameters on quality attributes in high shear wet granulation

SIF Badawy, AS Narang, KR LaMarche… - … of Pharmaceutical Wet …, 2019 - Elsevier
The mechanisms of the effect of process parameters on primary properties of granules
manufactured by wet granulation (size and density), bulk performance indicating properties …

A quantitative study of the effect of process parameters on key granule characteristics in a high shear wet granulation process involving a two component …

S Oka, O Kašpar, V Tokárová, K Sowrirajan… - Advanced Powder …, 2015 - Elsevier
The objective of the current work was to investigate the effect of liquid to solid ratio (L/S),
impeller speed and the wet massing time on the critical quality attributes of granules in a …

DEM simulation of a single screw granulator: The effect of liquid binder on granule properties

TB Arthur, NKG Sekyi, N Rahmanian - Chemical Engineering Research …, 2024 - Elsevier
The Caleva UK single-screw Variable Density Extruder (VDE) is a continuous powder
processing equipment known for spheronization and extrusion. Its suitability for granulation …

Investigation the iron ore fine granulation effects and particle adhesion behavior in a horizontal high-shear granulator

Y You, J Guo, G Li, X Lv, S Wu, Y Li, R Yang - Powder Technology, 2021 - Elsevier
This work presents a study of the granulation of iron fines in a horizontal high shear
granulator. Both experiments and DEM simulations were conducted to investigate the effect …

High shear seeded granulation: Its preparation mechanism, formulation, process, evaluation, and mathematical simulation

R Maharjan, SH Jeong - Powder Technology, 2020 - Elsevier
Seeded granulation is one of the recently adopted wet granulation techniques. The seeded
granules consist of high-density core nuclei and low-density particles layered on the outside …

Influence of spray nozzle aperture during high shear wet granulation on granule properties and its compression attributes

N Veronica, HP Goh, CYX Kang, CV Liew… - International Journal of …, 2018 - Elsevier
The distribution of granulating liquid is known to affect the high shear wet granulation
process but the impact of the spray nozzle attributes is still unclear. While homogenous …